LIFR anticorps (AA 45-188)

N° du produit ABIN7193531

Détail du produit anti-LIFR anticorps

Antigène: LIFR (Leukemia Inhibitory Factor Receptor alpha (LIFR))

Épitope: AA 45-188

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp LIFR est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Purification: purified

Immunogène: Purified recombinant fragment of human CD118 (AA: 45-188) expressed in E. coli.

Clone: 5D3G12

Isotype: IgG1

Information d'application

Indications d'application: WB:1:500 - 1:2000, FCM:1:200 - 1:400, ELISA:1:10000,

Restrictions: For Research Use only

Stockage

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: 4°C, -20°C for long term storage

Détails sur LIFR

Antigène: LIFR (Leukemia Inhibitory Factor Receptor alpha (LIFR))

Autre désignation: CD118 (LIFR Produits)

Synonymes: anticorps A230075M04Rik, anticorps AW061234, anticorps LIF, anticorps CD118, anticorps LIF-R, anticorps SJS2, anticorps STWS, anticorps SWS, anticorps leukemia inhibitory factor receptor, anticorps LIF receptor alpha, anticorps leukemia inhibitory factor receptor alpha, anticorps Lifr, anticorps LOC397451, anticorps LIFR

Sujet:

Description: This gene encodes a protein that belongs to the type I cytokine receptor family. This protein combines with a high-affinity converter subunit, gp130, to form a receptor complex that mediates the action of the leukemia inhibitory factor, a polyfunctional cytokine that is involved in cellular differentiation, proliferation and survival in the adult and the embryo. Mutations in this gene cause Schwartz-Jampel syndrome type 2, a disease belonging to the group of the bent-bone dysplasias. A translocation that involves the promoter of this gene, t(5,8)(p13,q12) with the pleiomorphic adenoma gene 1, is associated with salivary gland pleiomorphic adenoma, a common type of benign epithelial tumor of the salivary gland. Multiple splice variants encoding two different isoforms have been found for this gene.

Aliases: LIFR, SWS, SJS2, STWS, LIF-R

Poids moléculaire: 123.7 kDa

ID gène: 3977

Pathways: Signalistation JAK/STAT, Growth Factor Binding