HLA-DPB1 anticorps

N° du produit ABIN7268370

Détail du produit anti-HLA-DPB1 anticorps

Antigène: HLA-DPB1 (Major Histocompatibility Complex, Class II, DP beta 1 (HLA-DPB1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HLA-DPB1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Fonction: HLA-DPB1 Rabbit pAb

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein of Human HLA-DPB1.

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur HLA-DPB1

Antigène: HLA-DPB1 (Major Histocompatibility Complex, Class II, DP beta 1 (HLA-DPB1))

Autre désignation: HLA-DPB1 (HLA-DPB1 Produits)

Synonymes: anticorps PATR-DPB1, anticorps B-LB, anticorps B-LB2, anticorps B-LB21, anticorps BLB1, anticorps GSP-BLB1, anticorps DPB1, anticorps HLA-DP, anticorps HLA-DP1B, anticorps HLA-DPB, anticorps major histocompatibility complex, class II, DP beta 1, anticorps Major histocompatibility complex class II beta chain BLB1, anticorps PATR-DPB1, anticorps BLB1, anticorps HLA-DPB1

Sujet: HLA-DPB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta chain (DPB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules. [provided by RefSeq, Jul 2008],DPB1,HLA-DP,HLA-DP1B,HLA-DPB,HLA-DPB1,major histocompatibility complex,class II,DP beta 1,Immunology & Inflammation,HLA-DPB1

Poids moléculaire: 29kDa

ID gène: 3115

UniProt: P04440

Pathways: TCR Signaling, Cancer Immune Checkpoints