PPARGC1A anticorps (C-Term)

N° du produit ABIN7529539

Détail du produit anti-PPARGC1A anticorps

Antigène: PPARGC1A (Peroxisome Proliferator-Activated Receptor Gamma, Coactivator 1 alpha (PPARGC1A))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PPARGC1A est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Fonction: PGC1α Rabbit pAb

Séquence: FGEIEECTVN LRDDGDSYGF ITYRYTCDAF AALENGYTLR RSNETDFELY FCGRKQFFKS NYADLDSNSD DFDPASTKSK YDSLDFDSLL KEAQRSLRR

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: A synthetic peptide corresponding to a sequence within amino acids 700 to the C-terminus of human PGC1alpha (NP_037393.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PPARGC1A

Antigène: PPARGC1A (Peroxisome Proliferator-Activated Receptor Gamma, Coactivator 1 alpha (PPARGC1A))

Autre désignation: PPARGC1A (PPARGC1A Produits)

Synonymes: anticorps PPARGC1A, anticorps PPARGC1, anticorps A830037N07Rik, anticorps ENSMUSG00000079510, anticorps Gm11133, anticorps PGC-1, anticorps PGC-1v, anticorps Pgc-1alpha, anticorps Pgc1, anticorps Pgco1, anticorps Ppargc1, anticorps PGC1, anticorps PGC1A, anticorps LEM6, anticorps PGC-1(alpha), anticorps AVPGC-1ALPHA, anticorps PPARG coactivator 1 alpha, anticorps peroxisome proliferative activated receptor, gamma, coactivator 1 alpha, anticorps PPARG coactivator 1 alpha S homeolog, anticorps PPARGC1A, anticorps Ppargc1a, anticorps ppargc1a.S

Sujet: The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity.,PPARGC1A,LEM6,PGC-1(alpha),PGC-1alpha,PGC-1v,PGC1,PGC1A,PPARGC1,PPARG coactivator 1 alpha,PGC1 alpha,Epigenetics & Nuclear Signaling,Nuclear Receptor Signaling,Cancer,Signal Transduction,mTOR Signaling Pathway,Cell Biology & Developmental Biology,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial Biogenesis,Nucleotide metabolism,Molecular processes,AMPK Signaling Pathway,Endocrine and metabolic diseases,Diabetes,Obesity,Neuroscience,Neurodegenerative Diseases,Cardiovascular,Lipids,Fatty Acids,PPARGC1A

Poids moléculaire: 14kDa/30kDa/31kDa/33kDa/77kDa/89kDa/91kDa

ID gène: 10891

UniProt: Q9UBK2

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Carbohydrate Homeostasis, Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process, Smooth Muscle Cell Migration, Brown Fat Cell Differentiation