DIABLO anticorps

N° du produit ABIN7270177

Détail du produit anti-DIABLO anticorps

Antigène: DIABLO (Second Mitochondria-Derived Activator of Caspase (DIABLO))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp DIABLO est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Fonction: Smac/Diablo Rabbit mAb

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Monoclonal Antibodies

Purification: Affinity purification

Immunogène: A synthesized peptide derived from human Smac/Diablo

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur DIABLO

Antigène: DIABLO (Second Mitochondria-Derived Activator of Caspase (DIABLO))

Autre désignation: DIABLO (DIABLO Produits)

Synonymes: anticorps smac, anticorps smac3, anticorps diablo-s, anticorps 0610041G12Rik, anticorps 1700006L01Rik, anticorps AU040403, anticorps Smac, anticorps DFNA64, anticorps SMAC, anticorps DBO, anticorps XSmac, anticorps diablo, IAP-binding mitochondrial protein, anticorps diablo IAP-binding mitochondrial protein, anticorps diablo, IAP-binding mitochondrial protein L homeolog, anticorps diablo, anticorps Diablo, anticorps DIABLO, anticorps diablo.L

Sujet: This gene encodes an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and allows activation of caspases by binding to inhibitor of apoptosis proteins. Overexpression of the encoded protein sensitizes tumor cells to apoptosis. A mutation in this gene is associated with young-adult onset of nonsyndromic deafness-64. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013],DFNA64, SMAC,Apoptosis,Apoptosis_Death receptors & ligands,Apoptosis_Inhibition of Apoptosis,Apoptosis_Mitochondrial Control of Apoptosis,Cancer,Cell Biology & Developmental Biology,Death Receptor Signaling Pathway,Endocrine & Metabolism,Invasion and Metastasis,Mitochondrial metabolism,Mitochondrial metabolism_Mitochondrial markers,DIABLO

Poids moléculaire: 21kDa

ID gène: 56616

UniProt: Q9NR28

Pathways: Apoptose, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity