BAD anticorps (AA 1-50)

N° du produit ABIN7448932

Cet anticorps Lapin Polyclonal détecte spécifiquement BAD dans IHC et IF (p). Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour BAD anticorps (AA 1-50) (ABIN7448932)

Antigène: BAD (BCL2-Associated Agonist of Cell Death (BAD))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BAD est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-BAD anticorps

Épitope: AA 1-50

Fonction: Rabbit anti-BAD IHC Antibody, Affinity Purified

Homologie: Rat,Dog,Panda,Cat,Orangutan,Monkey,Gorilla,Chimpanzee,Small-eared galago,Thirteen-lined ground squirrel,White-tufted-ear marmoset,Naked mole rat,Crab-eating macaque

Purification: Affinity Purified

Immunogène: Between AA 1 and 50

Isotype: IgG

Information d'application

Indications d'application:

IHC-IF: 1:50 - 1:500

IHC: 1:100 - 1:500

Restrictions: For Research Use only

Stockage

Concentration: 100 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur BAD

Antigène: BAD (BCL2-Associated Agonist of Cell Death (BAD))

Autre désignation: BAD

Sujet: Background: BAD (Bcl2 agonist of cell death) is a member of the Bcl-2 family. Bcl-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with Bcl-xL and Bcl-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein [taken from NCBI Entrez Gene (GeneID:572)].

ID gène: 572

NCBI Accession: NP_004313

UniProt: Q92934

Pathways: Signalisation MAPK, Signalisation PI3K-Akt, Signalisation RTK, Apoptose, Fc-epsilon Receptor Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Hepatitis C, CXCR4-mediated Signaling Events