EPH Receptor A7 anticorps (EPHA7) (AA 203-253)

Details for Product anti-EPHA7 Antibody No. ABIN722005, Fournisseur: Connectez-vous pour afficher
Antigène
  • fc51g03
  • wu:fc51g03
  • si:dkey-23k6.1
  • EHK3
  • HEK11
  • Cek11
  • Ebk
  • Ehk3
  • Hek11
  • Mdk1
  • CEPHA7
  • EPH receptor A7
  • eph receptor A7
  • ephrin type-B receptor 1-B
  • Eph receptor A7
  • EPHA7
  • epha7
  • LOC100166161
  • Epha7
Épitope
AA 203-253
18
18
15
14
14
14
11
8
8
5
4
3
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
Reactivité
Humain, Souris, Rat (Rattus)
145
70
48
5
3
2
2
2
2
1
1
1
Hôte
Lapin
122
25
17
1
Clonalité
Polyclonal
Conjugué
Cet anticorp EPH Receptor A7 est non-conjugé
8
8
8
7
6
6
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
124
91
61
31
27
12
3
2
Options
Fournisseur
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Supplier Product No.
Connectez-vous pour afficher
Immunogène KLH conjugated synthetic peptide derived from human EphA7
Isotype IgG
Specificité There is a chance that this protein will cross-react with EphA4 based on a 73 % non-sequential sequence similarity.
Purification Purified by Protein A.
Autre désignation Eph Receptor A7 (EPHA7 Antibody Extrait)
Sujet

Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Among GPI-anchored ephrin-A ligands, EFNA5 is a cognate/functional ligand for EPHA7 and their interaction regulates brain development modulating cell-cell adhesion and repulsion. Has a repellent activity on axons and is for instance involved in the guidance of corticothalamic axons and in the proper topographic mapping of retinal axons to the colliculus. May also regulate brain development through a caspase(CASP3)-dependent proapoptotic activity. Forward signaling may result in activation of components of the ERK signaling pathway including MAP2K1, MAP2K2, MAPK1 AND MAPK3 which are phosphorylated upon activation of EPHA7.

Subcellular location: Extracellular

Synonyms: EHK3, EK11, EHK-3, HEK11, Ephrin type-A receptor 7, EPH homology kinase 3, EPH-like kinase 11, EPHA7

ID gène 2045
UniProt Q15375
Pathways Signalisation RTK
Indications d'application WB 1:100-1000
FCM 1:20-100
IHC-P 1:100-500
IF(IHC-P) 1:50-200
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Agent conservateur Sodium azide
Précaution d'utilisation This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Stock -20 °C
Stockage commentaire Store at -20°C
Date de péremption 12 months
Supplier Images
Immunohistochemistry (IHC) image for anti-EPH Receptor A7 (EPHA7) (AA 203-253) antibody (ABIN722005) Formalin-fixed and paraffin embedded mouse embryo labeled with Rabbit Anti EphA7/Eph ...
Immunohistochemistry (IHC) image for anti-EPH Receptor A7 (EPHA7) (AA 203-253) antibody (ABIN722005) Formalin-fixed and paraffin embedded rat brain labeled with Rabbit Anti EphA7/Eph rec...
Immunofluorescence (IF) image for anti-EPH Receptor A7 (EPHA7) (AA 203-253) antibody (ABIN722005) Formalin-fixed and paraffin-embedded rat testis labeled with Anti--EphA7/Eph receptor...
Flow Cytometry (FACS) image for anti-EPH Receptor A7 (EPHA7) (AA 203-253) antibody (ABIN722005) Mouse spleen cells probed with Rabbit Anti-Eph receptor A7 Polyclonal Antibody .
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-EPH Receptor A7 (EPHA7) (AA 203-253) antibody (ABIN722005) Formalin-fixed and paraffin embedded mouse embryo labeled with Rabbit Anti EphA7/Eph ...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-EPH Receptor A7 (EPHA7) (AA 203-253) antibody (ABIN722005) Formalin-fixed and paraffin embedded rat brain labeled with Rabbit Anti EphA7/Eph rec...
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