TARDBP anticorps (AA 21-120) (Cy5.5)
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- Antigène Voir toutes TARDBP Anticorps
- TARDBP (TAR DNA Binding Protein (TARDBP))
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Épitope
- AA 21-120
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Reactivité
- Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp TARDBP est conjugé à/à la Cy5.5
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Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Réactivité croisée
- Rat
- Homologie
- Human,Mouse,Cow,Chicken,Rabbit
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human TDP-43
- Isotype
- IgG
- Top Product
- Discover our top product TARDBP Anticorps primaire
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- Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- TARDBP (TAR DNA Binding Protein (TARDBP))
- Autre désignation
- TARDBP (TARDBP Produits)
- Synonymes
- anticorps TARDBP, anticorps TDP43, anticorps DKFZp459I2127, anticorps tardbp, anticorps ALS10, anticorps TDP-43, anticorps 1190002A23Rik, anticorps C85084, anticorps Tdp43, anticorps wu:fb77f02, anticorps wu:fc52g10, anticorps TAR DNA binding protein, anticorps Tardbp protein, anticorps TAR DNA binding protein L homeolog, anticorps TAR DNA-binding protein 43-like, anticorps TARDBP, anticorps tardbp, anticorps tardbp.L, anticorps Tardbp, anticorps LOC100621383
- Sujet
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Synonyms: ALS10, TDP-43, TAR DNA-binding protein 43, TARDBP, TDP43
Background: DNA and RNA-binding protein which regulates transcription and splicing. Involved in the regulation of CFTR splicing. It promotes CFTR exon 9 skipping by binding to the UG repeated motifs in the polymorphic region near the 3'-splice site of this exon. The resulting aberrant splicing is associated with pathological features typical of cystic fibrosis. May also be involved in microRNA biogenesis, apoptosis and cell division. Can repress HIV-1 transcription by binding to the HIV-1 long terminal repeat. Stabilizes the low molecular weight neurofilament (NFL) mRNA through a direct interaction with the 3' UTR.
- ID gène
- 23435
- UniProt
- Q13148
- Pathways
- Positive Regulation of Peptide Hormone Secretion
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