AP2B1 anticorps (AA 351-450)

N° du produit ABIN731138

Détail du produit anti-AP2B1 anticorps

Antigène: AP2B1 (Adaptor-Related Protein Complex 2, beta 1 Subunit (AP2B1))

Épitope: AA 351-450

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AP2B1 est non-conjugé

Application: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Dog,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human beta Adaptin

Isotype: IgG

Information d'application

Indications d'application: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur AP2B1

Antigène: AP2B1 (Adaptor-Related Protein Complex 2, beta 1 Subunit (AP2B1))

Autre désignation: beta Adaptin/AP2 beta (AP2B1 Produits)

Synonymes: anticorps 5-HT(2B), anticorps 5-HT2B, anticorps ADTB2, anticorps AP105B, anticorps AP2-BETA, anticorps CLAPB1, anticorps 1300012O03Rik, anticorps AI788979, anticorps fa16e07, anticorps wu:fa16c06, anticorps wu:fa16e07, anticorps wu:fc18c08, anticorps zgc:55659, anticorps 5-hydroxytryptamine receptor 2B, anticorps adaptor related protein complex 2 beta 1 subunit, anticorps adaptor-related protein complex 2, beta 1 subunit, anticorps adaptor related protein complex 2 beta 1 subunit L homeolog, anticorps HTR2B, anticorps AP2B1, anticorps Ap2b1, anticorps ap2b1, anticorps ap2b1.L

Sujet:

Synonyms: Adaptin beta 1 beta prime, _-Adaptin, Adaptin _1, Adaptin-_1, Adaptin beta 2 beta, Adaptin beta 2, Adaptin, beta 2 beta, Adaptor protein complex AP 1 beta 1 subunit, Adaptor related protein complex 1 beta 1 subunit, Adaptor related protein complex 1, beta 1 subunit, Adaptor related protein complex 2 beta 1 subunit, Adaptor related protein complex 2, beta 1 subunit, ADTB 1, ADTB 2, ADTB1, ADTB2, AP 1 complex subunit beta 1, AP 105A, AP 105B, AP 2 complex subunit beta 1, AP1 Beta, AP1 complex subunit beta 1, AP105A, AP105B, AP1B1, AP2 beta, AP2 complex subunit beta 1, AP2B1, AP2beta, BAM 22, BAM22, Beta adaptin, Beta prime adaptin, Beta1 adaptin, Beta2 adaptin, CLAPB 1, CLAPB 2, CLAPB1, CLAPB2, Clathrin assembly protein complex 1, Clathrin assembly protein complex 1 beta large chain, Clathrin assembly protein complex 2 beta large chain, Clathrin associated/assembly/adaptor protein large beta 1, Clathrin associated/assembly/adaptor protein large beta 2, DKFZp781K0743, Golgi adaptor HA1/AP1 adaptin beta subunit, Plasma membrane adaptor HA2/AP2 adaptin beta subunit, Plasma membrane adaptor HA2/AP2 adaptor beta subunit, Plasma membrane adaptor HA2/AP2.

Background: Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limbs and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP2 beta appears to be required for normal face and limb development and for proper terminal differentiation and function of renal tubular epithelia.

ID gène: 2971

Pathways: EGFR Signaling Pathway, Neurotrophin Signaling Pathway, EGFR Downregulation