PKC alpha anticorps (AA 75-103)
Aperçu rapide pour PKC alpha anticorps (AA 75-103) (ABIN7876726)
Antigène
Voir toutes PKC alpha (PKCa) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 75-103
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Fonction
- PKC alpha Antibody / PRKCA
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Purification
- Purified
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Immunogène
- A portion of amino acids 75-103 from the human protein was used as the immunogen for the PKC alpha antibody.
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Isotype
- Ig Fraction
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Indications d'application
- The stated application concentrations are suggested starting points. Titration of the PKC alpha antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Aliquot the PKC alpha antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- PKC alpha (PKCa) (Protein Kinase C, alpha (PKCa))
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Autre désignation
- PKC alpha
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Sujet
- PRKCA is a calcium-activated, phospholipid-dependent, serine-and threonine-specific enzyme. It may play a role in cell motility by phosphorylating CSPG4. PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters.
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UniProt
- P17252
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Pathways
- Signalisation WNT, TCR Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Cell-Cell Junction Organization, Regulation of G-Protein Coupled Receptor Protein Signaling, G-protein mediated Events, Signaling Events mediated by VEGFR1 and VEGFR2, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, VEGFR1 Specific Signals, VEGF Signaling
Antigène
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