PLCD1 anticorps (AA 14-549) (HRP)

N° du produit ABIN8022164

Cet anticorps Lapin Polyclonal détecte spécifiquement PLCD1 dans WB, ELISA et IHC. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour PLCD1 anticorps (AA 14-549) (HRP) (ABIN8022164)

Antigène: PLCD1 (phospholipase C, delta 1 (PLCD1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PLCD1 est conjugé à/à la HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-PLCD1 anticorps (HRP)

Épitope: AA 14-549

Fonction: Anti-PLCD1 Antibody HRP Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: Human PLCD1 shares 92.2%,92.5% amino acid (aa) sequence identity with mouse,rat PLCD1,respectively.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human PLCD1 recombinant protein (Position: Q14-R549). Human PLCD1 shares 92.2% and 92.5% amino acid (aa) sequence identity with mouse and rat PLCD1, respectively.

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur PLCD1

Antigène: PLCD1 (phospholipase C, delta 1 (PLCD1))

Autre désignation: PLCD1

Sujet:

Background: This gene encodes a member of the phospholipase C family. Phospholipase C isozymes play critical roles in intracellular signal transduction by catalyzing the hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2) into the second messengers diacylglycerol (DAG) and inositol triphosphate (IP3). The encoded protein functions as a tumor suppressor in several types of cancer, and mutations in this gene are a cause of hereditary leukonychia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene Full Name: phospholipase C delta 1

ID gène: 5333

UniProt: P51178

Pathways: Signalisation WNT, Myometrial Relaxation and Contraction, Regulation of Carbohydrate Metabolic Process