PLCD1 anticorps (AA 14-549) (APC)

N° du produit ABIN8022165

L’anticorps anti-PLCD1 Polyclonal Lapin est utilisé pour la détection de PLCD1 dans des échantillons de Humain, Souris et Rat. Il a été validé pour FACS.

Aperçu rapide pour PLCD1 anticorps (AA 14-549) (APC) (ABIN8022165)

Antigène: PLCD1 (phospholipase C, delta 1 (PLCD1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PLCD1 est conjugé à/à la APC

Application: Flow Cytometry (FACS)

Détail du produit anti-PLCD1 anticorps (APC)

Épitope: AA 14-549

Fonction: Anti-PLCD1 Antibody APC Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: Human PLCD1 shares 92.2%,92.5% amino acid (aa) sequence identity with mouse,rat PLCD1,respectively.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human PLCD1 recombinant protein (Position: Q14-R549). Human PLCD1 shares 92.2% and 92.5% amino acid (aa) sequence identity with mouse and rat PLCD1, respectively.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur PLCD1

Antigène: PLCD1 (phospholipase C, delta 1 (PLCD1))

Autre désignation: PLCD1

Sujet:

Background: This gene encodes a member of the phospholipase C family. Phospholipase C isozymes play critical roles in intracellular signal transduction by catalyzing the hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2) into the second messengers diacylglycerol (DAG) and inositol triphosphate (IP3). The encoded protein functions as a tumor suppressor in several types of cancer, and mutations in this gene are a cause of hereditary leukonychia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene Full Name: phospholipase C delta 1

ID gène: 5333

UniProt: P51178

Pathways: Signalisation WNT, Myometrial Relaxation and Contraction, Regulation of Carbohydrate Metabolic Process