Tamalin/GRASP anticorps (AA 814-818)

N° du produit ABIN871663

Détail du produit anti-Tamalin/GRASP anticorps

Antigène: Tamalin/GRASP (GRASP) (GRP1 (General Receptor For phosphoinositides 1)-Associated Scaffold Protein (GRASP))

Épitope: AA 814-818

Reactivité: Souris, Rat, Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Tamalin/GRASP est non-conjugé

Application: Western Blotting (WB)

Specificité: The antibody detects endogenous level of total GRASP protein.

Purification: Affinity purified

Immunogène: Peptide sequence around AA 814-818 (Q-E-I-V-R ) derived from Rat GRASP. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.

Information d'application

Indications d'application: Western blotting: 1:500-1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Détails sur Tamalin/GRASP

Antigène: Tamalin/GRASP (GRASP) (GRP1 (General Receptor For phosphoinositides 1)-Associated Scaffold Protein (GRASP))

Autre désignation: GRASP (GRASP Produits)

Synonymes: anticorps GRASP, anticorps tamalin, anticorps TAMALIN, anticorps general receptor for phosphoinositides 1 associated scaffold protein, anticorps GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein, anticorps GRASP, anticorps grasp, anticorps Grasp

Sujet: GRASP (GRP1-associated scaffold protein, tamalin) is a 395 amino acid protein encoded by the human gene GRASP . GRASP is a scaffold protein that com-prises multiple protein-interacting domains, including a 95 kDa postsynaptic density protein (PSD-95)/discs-large/ZO-1 (PDZ) domain, a leucine-zipper region and a carboxyl-terminal PDZ-binding motif. GRASP is involved with intracellular trafficking and contributes to the macromolecular organization of group 1 metabotropic glutamate receptors (mGluRs) at synapses. GRASP forms a heteromer composed of GRASP , PSCD2 and at least one mGluR-1. It also interacts with PSCD3, mGluR-2, mGluR-3 and mGluR-5. GRASP is highly expressed in brain and has lower levels of expression in lung, heart, embryo, kidney and ovary.

Poids moléculaire: 95 kDa

ID gène: 56850

NCBI Accession: NP_064522

UniProt: Q9JHZ4