HNRNPA1 anticorps (AA 190-194)

N° du produit ABIN871695

Détail du produit anti-HNRNPA1 anticorps

Antigène: HNRNPA1 (Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1))

Épitope: AA 190-194

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HNRNPA1 est non-conjugé

Application: Western Blotting (WB)

Specificité: The antibody detects endogenous levels of total hnRNP A1 protein.

Purification: Affinity purified

Immunogène: Peptide sequence around AA 190-194 (S-S-S-Q-R) derived from Human hnRNP A1. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.

Information d'application

Indications d'application: Western blotting: 1:500-1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Détails sur HNRNPA1

Antigène: HNRNPA1 (Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1))

Autre désignation: hnRNP A1 (HNRNPA1 Produits)

Synonymes: anticorps HNRPA1, anticorps HNRPA1L3, anticorps hnRNP A1, anticorps hnRNP-A1, anticorps hnrpa1, anticorps TPT1P, anticorps HNRNPA1, anticorps D15Ertd119e, anticorps Hdp, anticorps Hnrpa1, anticorps hnrnp-A1, anticorps ROA1, anticorps zgc:66127, anticorps heterogeneous nuclear ribonucleoprotein A1, anticorps heterogeneous nuclear ribonucleoprotein A1b, anticorps Heterogeneous nuclear ribonucleoprotein A1, anticorps heterogeneous nuclear ribonucleoprotein A1 S homeolog, anticorps ribonucleoprotein A1a, anticorps heterogeneous nuclear ribonucleoprotein A1-like, anticorps heterogeneous nuclear ribonucleoprotein A1a, anticorps HNRNPA1, anticorps hnrnpa1b, anticorps LOC100101226, anticorps roa1, anticorps Hnrnpa1, anticorps hnrnpa1.S, anticorps hnrnpa1, anticorps LOC100359118, anticorps hnrnpa1a

Sujet: Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) is a member of the hnRNP A/B family of related RNA binding proteins that bind pre-mRNA and are involved in the processing, metabolism and transport of nuclear pre-mRNA transcripts . hnRNP A1 regulates the alternative splicing of c-Src, c-H-Ras and modifies initiation of translation of the fibroblast growth factor 2 mRNA. hnRNP A1 expression level is elevated in many cancers, knockdown of hnRNP A1 leads to apoptosis in various cancer cells . Although predominantly nuclear, hnRNP A1 is continually transported from the nucleus to the cytoplasm where it disassociates from mRNA and is rapidly re-imported into the nucleus . hnRNP A1 binds to cis-acting repressive sequences (CRS) of HIV-1 to influence HIV-1 production . HIV-1 enhances hnRNP A1 expression and promotes the relocalization of hnRNP A1 to the cytoplasm ,

Poids moléculaire: 39 kDa

ID gène: 3178

NCBI Accession: NP_002127

UniProt: P09651