MEK1/2 anticorps (pSer218, pSer222) (Alexa Fluor 488)

N° du produit ABIN874925

Détail du produit anti-MEK1/2 anticorps (Alexa Fluor 488)

Antigène: MEK1/2 (MAP2K1/2) (Mitogen-Activated Protein Kinase Kinase 1/2 (MAP2K1/2))

Épitope: pSer218, pSer222

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MEK1/2 est conjugé à/à la Alexa Fluor 488

Application: Western Blotting (WB)

Specificité: These phosphorylation sites are homologous to Ser222 + Ser226 in MEK2 and are the same across the listed species.

Réactivité croisée: Humain

Homologie: Mouse,Rat,Dog,Cow,Pig,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human MEK1 around the phosphorylation site of Ser218/222

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur MEK1/2

Antigène: MEK1/2 (MAP2K1/2) (Mitogen-Activated Protein Kinase Kinase 1/2 (MAP2K1/2))

Autre désignation: Mek1/2 (MAP2K1/2 Produits)

Sujet:

Synonyms: MAP2K1phospho S218/S222, Dual specicity mitogen activated protein kinase kinase 1, ERK activator kinase 1, MAP kinase kinase 1, MAP kinase/Erk kinase 1, MAP/Erk kinase 1, Map2K1, MAPK/ERK kinase 1, MAPKK 1, MAPKK1, MEK 1, MEKK1, Mitogen activated protein kinase kinase 1, MKK 1, MKK1, PRKMK 1, PRKMK1,Protein kinase mitogen activated kinase 1 MAP kinase kinase 1, Protein kinase mitogen activated kinase 1, Protein kinase mitogen activated, kinase 1.

Background: The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development.

ID gène: 56045605