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Collagen IV anticorps (AA 1571-1669) (Alexa Fluor 488)

COL4 Reactivité: Humain, Souris, Rat, Porc WB, FACS, IF (p), IF (cc) Hôte: Lapin Polyclonal Alexa Fluor 488
N° du produit ABIN891716
  • Antigène Voir toutes Collagen IV (COL4) Anticorps
    Collagen IV (COL4) (Collagen, Type IV (COL4))
    Épitope
    • 16
    • 15
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1571-1669
    Reactivité
    • 90
    • 42
    • 40
    • 22
    • 16
    • 11
    • 5
    • 2
    Humain, Souris, Rat, Porc
    Hôte
    • 59
    • 27
    • 13
    Lapin
    Clonalité
    • 71
    • 28
    Polyclonal
    Conjugué
    • 50
    • 10
    • 7
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Cet anticorp Collagen IV est conjugé à/à la Alexa Fluor 488
    Application
    • 61
    • 50
    • 31
    • 28
    • 27
    • 27
    • 25
    • 25
    • 20
    • 10
    • 9
    • 8
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
     Réactivité croisée
    Humain, Souris, Porc, Rat
    Homologie
    Dog,Cow,Horse,Chicken,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human Collagen alpha-1(IV) chain
    Isotype
    IgG
    Top Product
    Discover our top product COL4 Anticorps primaire
  • Indications d'application
    FCM 1:20-100
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Belair, Wolf, Wood, Ren, Grindstaff, Padgett, Swank, MacMillan, Fisher, Winnik, Abbott: "Engineering human cell spheroids to model embryonic tissue fusion in vitro." dans: PLoS ONE, Vol. 12, Issue 9, pp. e0184155, (2017) (PubMed).

  • Antigène
    Collagen IV (COL4) (Collagen, Type IV (COL4))
    Autre désignation
    Collagen 4 (COL4 Produits)
    Synonymes
    anticorps collagen, type IV, anticorps Let-2
    Sujet

    Synonyms: ICH, HANAC, POREN1, arresten, Collagen alpha-1(IV) chain, COL4A1

    Background: Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen. Arresten, comprising the C-terminal NC1 domain, inhibits angiogenesis and tumor formation. The C-terminal half is found to possess the anti-angiogenic activity. Specifically inhibits endothelial cell proliferation, migration and tube formation. Inhibits expression of hypoxia-inducible factor 1alpha and ERK1/2 and p38 MAPK activation. Ligand for alpha1/beta1 integrin.

    ID gène
    1282
    UniProt
    P02462
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