PSMD14 anticorps (AA 101-200) (Alexa Fluor 488)

N° du produit ABIN905319

Détail du produit anti-PSMD14 anticorps (Alexa Fluor 488)

Antigène: PSMD14 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 14 (PSMD14))

Épitope: AA 101-200

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PSMD14 est conjugé à/à la Alexa Fluor 488

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat,Cow,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human MAD1

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur PSMD14

Antigène: PSMD14 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 14 (PSMD14))

Autre désignation: Mad1 (PSMD14 Produits)

Synonymes: anticorps PAD1, anticorps POH1, anticorps RPN11, anticorps 2610312C03Rik, anticorps 3200001M20Rik, anticorps AA986732, anticorps Pad1, anticorps Poh1, anticorps rpm11, anticorps zgc:162272, anticorps proteasome 26S subunit, non-ATPase 14, anticorps proteasome (prosome, macropain) 26S subunit, non-ATPase, 14, anticorps 26S proteasome non-ATPase regulatory subunit 14, anticorps proteasome 26S subunit, non-ATPase 14 L homeolog, anticorps 26S proteasome-associated pad1 homolog, anticorps PSMD14, anticorps Psmd14, anticorps rpn-11, anticorps psmd14, anticorps psmd14.L

Sujet:

Synonyms: mitosis arrest deficiency 1, hMAD1, HsMAD1, MAD1L1, Mitotic arrest deficient 1, Mitotic checkpoint MAD1 protein homolog, Mitotic spindle assembly checkpoint protein MAD1, PIG9, Tax binding protein 181, TP53I9 , Tumor protein p53 inducible protein 9, TXBP181, MD1L1_HUMAN.

Background: spindle microtubules. The checkpoint works by inhibiting the activity of the anaphase promoting complex, thereby preventing the degradation of several cell cycle regulators. Like other spindle checkpoint mutants, MAD1 loss-of-function mutants are sensitive to benomyl and cannot delay cell division in response to spindle depolymerization. Mad1p becomes hyperphosphorylated upon spindle depolymerization.

ID gène: 8379

Pathways: Mitotic G1-G1/S Phases, DNA Replication, M Phase, Positive Regulation of Endopeptidase Activity, Synthesis of DNA, Ubiquitin Proteasome Pathway