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Menin anticorps (AA 501-615) (Alexa Fluor 488)

MEN1 Reactivité: Humain, Souris, Rat IF (cc), IF (p) Hôte: Lapin Polyclonal Alexa Fluor 488
N° du produit ABIN906146
  • Antigène Voir toutes Menin (MEN1) Anticorps
    Menin (MEN1) (Multiple Endocrine Neoplasia 1 (MEN1))
    Épitope
    • 14
    • 7
    • 6
    • 6
    • 6
    • 6
    • 6
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 501-615
    Reactivité
    • 74
    • 30
    • 23
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 67
    • 5
    • 2
    • 1
    Lapin
    Clonalité
    • 70
    • 5
    Polyclonal
    Conjugué
    • 37
    • 7
    • 7
    • 6
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Menin est conjugé à/à la Alexa Fluor 488
    Application
    • 55
    • 39
    • 23
    • 17
    • 12
    • 12
    • 8
    • 8
    • 7
    • 3
    • 1
    • 1
    • 1
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
     Réactivité croisée
    Humain, Souris, Rat
    Homologie
    Dog,Cow,Pig
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human Menin
    Isotype
    IgG
    Top Product
    Discover our top product MEN1 Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    Menin (MEN1) (Multiple Endocrine Neoplasia 1 (MEN1))
    Autre désignation
    Menin (MEN1 Produits)
    Synonymes
    anticorps MEAI, anticorps SCG2, anticorps menin, anticorps meai, anticorps scg2, anticorps AW045611, anticorps menin 1, anticorps menin 1 L homeolog, anticorps multiple endocrine neoplasia I, anticorps multiple endocrine neoplasia 1, anticorps MEN1, anticorps men1, anticorps men1.L, anticorps Men1
    Sujet

    Synonyms: MEAI, SCG2, Menin, MEN1

    Background: Essential component of a MLL/SET1 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3 (H3K4). Functions as a transcriptional regulator. Binds to the TERT promoter and represses telomerase expression. Plays a role in TGFB1-mediated inhibition of cell-proliferation, possibly regulating SMAD3 transcriptional activity. Represses JUND-mediated transcriptional activation on AP1 sites, as well as that mediated by NFKB subunit RELA. Positively regulates HOXC8 and HOXC6 gene expression. May be involved in normal hematopoiesis through the activation of HOXA9 expression (By similarity). May be involved in DNA repair.

    ID gène
    4221
    UniProt
    O00255
    Pathways
    Chromatin Binding, Positive Regulation of Endopeptidase Activity
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