MFN2 anticorps (AA 1-120) (Alexa Fluor 647)
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- Antigène Voir toutes MFN2 Anticorps
- MFN2 (Mitofusin 2 (MFN2))
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Épitope
- AA 1-120
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Reactivité
- Humain, Souris, Rat, Lapin
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp MFN2 est conjugé à/à la Alexa Fluor 647
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Application
- Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Réactivité croisée
- Humain, Souris, Lapin, Rat
- Homologie
- Dog,Cow,Pig,Horse,Chicken
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human Mitofusin 2
- Isotype
- IgG
- Top Product
- Discover our top product MFN2 Anticorps primaire
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- Indications d'application
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FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- MFN2 (Mitofusin 2 (MFN2))
- Autre désignation
- Mitofusin 2 (MFN2 Produits)
- Synonymes
- anticorps CG3869, anticorps Dmel\\CG3869, anticorps MARF, anticorps Marf-1, anticorps Mfn, anticorps anon-WO0125274.3, anticorps dMFN, anticorps dMfn, anticorps dmfn, anticorps marf, anticorps mfn, anticorps mfn2, anticorps MFN2, anticorps hsg, anticorps cmt2a, anticorps cprp1, anticorps cmt2a2, anticorps CMT2A, anticorps CMT2A2, anticorps CPRP1, anticorps HSG, anticorps D630023P19Rik, anticorps Fzo, anticorps mg:cb01g09, anticorps si:dkeyp-104h9.2, anticorps wu:fb79a11, anticorps mitofusin 2, anticorps Mitochondrial assembly regulatory factor, anticorps mitofusin-2, anticorps mitofusin 2 L homeolog, anticorps MFN2, anticorps Marf, anticorps mfn2, anticorps LOC100186475, anticorps Mfn2, anticorps mfn2.L
- Sujet
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Synonyms: HSG, MARF, CMT2A, CPRP1, CMT2A2, Mitofusin-2, Transmembrane GTPase MFN2, MFN2, KIAA0214
Background: Essential transmembrane GTPase, which mediates mitochondrial fusion. Fusion of mitochondria occurs in many cell types and constitutes an important step in mitochondria morphology, which is balanced between fusion and fission. MFN2 acts independently of the cytoskeleton. It therefore plays a central role in mitochondrial metabolism and may be associated with obesity and/or apoptosis processes. Overexpression induces the formation of mitochondrial networks. Plays an important role in the regulation of vascular smooth muscle cell proliferation. Involved in the clearance of damaged mitochondria via selective autophagy (mitophagy). Is required for PARK2 recruitment to dysfunctional mitochondria. Involved in the control of unfolded protein response (UPR) upon ER stress including activation of apoptosis and autophagy during ER stress. Acts as an upstream regulator of EIF2AK3 and suppresses EIF2AK3 activation under basal conditions.
- ID gène
- 9927
- UniProt
- O95140
- Pathways
- Skeletal Muscle Fiber Development
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