MNAT1 anticorps (AA 51-150) (HRP)

N° du produit ABIN906756

Détail du produit anti-MNAT1 anticorps (HRP)

Antigène: MNAT1 (Menage A Trois Homolog 1, Cyclin H Assembly Factor (Xenopus Laevis) (MNAT1))

Épitope: AA 51-150

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MNAT1 est conjugé à/à la HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Souris, Rat

Homologie: Human,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human MNAT1

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur MNAT1

Antigène: MNAT1 (Menage A Trois Homolog 1, Cyclin H Assembly Factor (Xenopus Laevis) (MNAT1))

Autre désignation: MNAT1 (MNAT1 Produits)

Synonymes: anticorps F6I18.270, anticorps F6I18_270, anticorps Afu4g08900, anticorps E130115E11Rik, anticorps MAT1, anticorps P36, anticorps zgc:101599, anticorps CAP35, anticorps RNF66, anticorps TFB3, anticorps cyclin-dependent kinase-activating kinase assembly factor-related / CDK-activating kinase assembly factor-like protein, anticorps CDK-activating kinase assembly factor MAT1, anticorps MNAT1, CDK activating kinase assembly factor, anticorps menage a trois 1, anticorps MNAT CDK-activating kinase assembly factor 1, anticorps MNAT1, CDK activating kinase assembly factor L homeolog, anticorps AT4G30820, anticorps AFUA_4G08900, anticorps NFIA_107260, anticorps CpipJ_CPIJ001565, anticorps AFLA_110530, anticorps BDBG_00548, anticorps TERG_06789, anticorps Tsp_08309, anticorps mnat1, anticorps Mnat1, anticorps MNAT1, anticorps mnat1.L

Sujet:

Synonyms: MAT1, TFB3, CAP35, RNF66, CDK-activating kinase assembly factor MAT1, CDK7/cyclin-H assembly factor, Cyclin-G1-interacting protein, Menage a trois, RING finger protein 66, RING finger protein MAT1, p35, p36, MNAT1

Background: Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II.

ID gène: 4331

UniProt: P51948

Pathways: Cycle Cellulaire, Mitotic G1-G1/S Phases, M Phase