TLR3 anticorps
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- Antigène Voir toutes TLR3 Anticorps
- TLR3 (Toll-Like Receptor 3 (TLR3))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp TLR3 est non-conjugé
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Application
- Western Blotting (WB), Flow Cytometry (FACS)
- Specificité
- Reacts with TLR3.
- Stérilité
- 0.2 μm filtered
- Isotype
- IgG1
- Top Product
- Discover our top product TLR3 Anticorps primaire
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- Indications d'application
- Flow cytometry: (intracellular) Use at a 1:10 dilution. Western blot: Use at a 1:10 dilution.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- 1 mL of 0.2 µm sterile filtered antibody solution at 100 µg/mL in PBS containing 0.1% protein stabilizer.
- Stock
- 4 °C
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- Antigène
- TLR3 (Toll-Like Receptor 3 (TLR3))
- Autre désignation
- TLR3 (TLR3 Produits)
- Synonymes
- anticorps CD283, anticorps IIAE2, anticorps AI957183, anticorps zgc:123006, anticorps toll like receptor 3, anticorps toll-like receptor 3, anticorps TLR3, anticorps Tlr3, anticorps tlr3
- Sujet
- Toll-like receptors (TLR) are highly conserved throughout evolution and have been implicated in the innate defence to many pathogens. In Drosophila toll is required for the anti-fungal response, while the related 18-wheeler is involved in antibacterial defences. In mammals, TLR identified as type I transmembrane signalling receptors with pattern recognition capabilies, have been implicated in the innate host defence to pathogens. As investigated so far all functional characterized TLR signal via the TLR/IL-1 receptor (IL-1R) pathway where recruitment of MyD88 seems to be essential. Viral replication within infected cells results in generation of dsRNA which can stimulate immune cells. Recent data show that TLR3 acts as a receptor involved in the recognition of dsRNA, indicating a role for TLR3 in viral recognition and innate defence.
- Pathways
- Signalisation TLR, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades
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