BAD anticorps (C-Term)

N° du produit ABIN927291

Cet anticorps anti-BAD Polyclonal Lapin (ABIN927291) détecte spécifiquement BAD dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Boeuf (Vache) et Chien.

Aperçu rapide pour BAD anticorps (C-Term) (ABIN927291)

Antigène: BAD (BCL2-Associated Agonist of Cell Death (BAD))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BAD est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-BAD anticorps

Épitope: C-Term

Réactivité croisée: Souris, Rat (Rattus), Boeuf (Vache), Chien

Purification: Purified

Immunogène: BAD antibody was raised in rabbit using the C terminal of BAD as the immunogen

Information d'application

Indications d'application: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Commentaires:

BAD Blocking Peptide, (ABIN5612269), is also available for use as a blocking control in assays to test for specificity of this BAD antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Détails sur BAD

Antigène: BAD (BCL2-Associated Agonist of Cell Death (BAD))

Autre désignation: BAD

Sujet: BAD is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform. Synonyms: Polyclonal BAD antibody, Anti-BAD antibody, BCL2-antagonist of cell death antibody, BBC2 antibody, BCL2L8 antibody.

Pathways: Signalisation MAPK, Signalisation PI3K-Akt, Signalisation RTK, Apoptose, Fc-epsilon Receptor Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Hepatitis C, CXCR4-mediated Signaling Events