TXNIP anticorps (Middle Region)

N° du produit ABIN929118

Détail du produit anti-TXNIP anticorps

Antigène: TXNIP (Thioredoxin Interacting Protein (TXNIP))

Épitope: Middle Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TXNIP est non-conjugé

Application: Western Blotting (WB)

Purification: Purified

Immunogène: TXNIP antibody was raised in rabbit using the middle region of TXNIP as the immunogen

Information d'application

Indications d'application: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Commentaires:

TXNIP Blocking Peptide, catalog no. 33R-9486, is also available for use as a blocking control in assays to test for specificity of this TXNIP antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Détails sur TXNIP

Antigène: TXNIP (Thioredoxin Interacting Protein (TXNIP))

Autre désignation: TXNIP (TXNIP Produits)

Synonymes: anticorps EST01027, anticorps HHCPA78, anticorps THIF, anticorps VDUP1, anticorps Gm348, anticorps Trf3, anticorps TBP2, anticorps TRF3, anticorps 1200008J08Rik, anticorps AA682105, anticorps Hyplip1, anticorps Tbp-2, anticorps Vdup1, anticorps sb:cb368, anticorps txnip, anticorps thioredoxin interacting protein, anticorps TATA box binding protein like 2, anticorps TATA-box binding protein like 2, anticorps thioredoxin interacting protein L homeolog, anticorps thioredoxin interacting protein a, anticorps TXNIP, anticorps Tbpl2, anticorps TBPL2, anticorps Txnip, anticorps txnip.L, anticorps txnip, anticorps txnipa

Sujet: TXNIP may act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. It interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. It functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. It is required for the maturation of natural killer cells. Synonyms: Polyclonal TXNIP antibody, Anti-TXNIP antibody, thioredoxin interacting protein antibody, EST01027 antibody, HHCPA78 antibody, THIF antibody, VDUP1 antibody.

Pathways: Protein targeting to Nucleus, Platelet-derived growth Factor Receptor Signaling, Inflammasome