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CBFA2T2 anticorps (N-Term)
CBFA2T2
Reactivité: Humain
WB, EIA
Hôte: Lapin
Polyclonal
unconjugated
Détail du produit anti-CBFA2T2 anticorps
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Antigène
Voir toutes CBFA2T2 Anticorps
CBFA2T2
(Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 2 (CBFA2T2))
Épitope
Tous les épitopes à travers CBFA2T2 Anticorps.
AA 1-30, N-Term
Reactivité
Toutes les réactivités sur CBFA2T2 Anticorps
Humain
Hôte
Toutes les hôtes sur CBFA2T2 Anticorps
Lapin
Clonalité
Toutes les clonalités sur CBFA2T2 Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers CBFA2T2 Anticorps
Cet anticorp CBFA2T2 est non-conjugé
Application
Tous les applications à travers CBFA2T2 Anticorps.
Western Blotting (WB), Enzyme Immunoassay (EIA)
Specificité
This antibody reacts to CBFA2T2.
Réactivité croisée (Details)
Species reactivity (tested):Human.
Purification
Affinity chromatography on Protein A
Immunogène
KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human CBFA2T2
Isotype
Ig Fraction
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Alternatives
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Information d'application
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Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
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Format
Liquid
Concentration
0.25 mg/mL
Buffer
PBS, 0.09 % (W/V) sodium azide
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Avoid repeated freezing and thawing.
Stock
4 °C/-20 °C
Stockage commentaire
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Détails sur CBFA2T2
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Antigène
CBFA2T2
(Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 2 (CBFA2T2))
Autre désignation
CBFA2T2 (CBFA2T2 Produits )
Synonymes
anticorps MTGR1, anticorps A430091M07, anticorps C330013D05Rik, anticorps Cbfa2t2h, anticorps EHT, anticorps ZMYND3, anticorps p85, anticorps XETOR, anticorps cbfa2t2-a, anticorps CBFA2/RUNX1 translocation partner 2, anticorps core-binding factor, runt domain, alpha subunit 2, translocated to, 2 (human), anticorps CBFA2/RUNX1 translocation partner 2 L homeolog, anticorps Cbfa2t2, anticorps CBFA2T2, anticorps cbfa2t2.L
Sujet
In acute myeloid leukemia, especially in the M2 subtype, the t(8,21)(q22,q22) translocation is one of the most frequent karyotypic abnormalities. The translocation produces a chimeric gene made up of the 5'-region of the RUNX1 (AML1) gene fused to the 3'-region of the CBFA2T1 (MTG8) gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. The protein encoded by this gene binds to the AML1-MTG8 complex and may be important in promoting leukemogenesis. Several transcript variants are thought to exist for this gene, but the full-length natures of only three have been described.Synonyms: EHT, ETO homologous on chromosome 20, MTG8-like protein, MTG8-related protein 1, MTGR1, Myeloid translocation-related protein 1, p85
Poids moléculaire
67133 Da
ID gène
9139
NCBI Accession
NP_001028171
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