C9 anticorps

N° du produit ABIN951643

Détail du produit anti-C9 anticorps

Antigène: C9 (Complement Component C9 (C9))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp C9 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: Recognizes Complement C9

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Ammonium Sulfate Precipitation

Immunogène: Protein purified from Human plasma.

Clone: 6-40E-010

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: HEPES with 0.15 M NaCl, 0.01 % BSA, 0.03 % Sdium Azide and 50 % Glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur C9

Antigène: C9 (Complement Component C9 (C9))

Autre désignation: Complement C9 (C9 Produits)

Synonymes: anticorps LOC100037951, anticorps LOC100136130, anticorps c9, anticorps wu:fb60b05, anticorps wu:fd50e04, anticorps zgc:112272, anticorps complement C9, anticorps complement component 9, anticorps complement component 9 L homeolog, anticorps C9, anticorps c9, anticorps c9.L

Sujet: C9 is synthesised in the liver and monocytes, and is a plasma protein consisting of a single polypeptide chain of molecular weight 71 kDa. Normal plasma concentration is 60 mg/L. C9 forms part of the membrane attack complex (MAC) the cytolytic terminal complex of the complement pathways. C9 binds to the membrane associated C5b-8, binding of C9 to C5b-8 leads to the circular polymerisation of 12-18 C9 Molecules. This is the basis of the hydrophilic, proteinwalled, trans-membrane channel formed by the MAC, which leads to cell lysis and destruction.Synonyms: Complement 9, Complement component C9

ID gène: 735

NCBI Accession: NP_001728

UniProt: P02748

Pathways: Système du Complément