TLE1 anticorps (Middle Region)

N° du produit ABIN955230

Détail du produit anti-TLE1 anticorps

Antigène: TLE1 (Transducin-Like Enhancer of Split 1 (E(sp1) Homolog, Drosophila) (TLE1))

Épitope: AA 206-236, Middle Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TLE1 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody detects TLE1 (Center).

Réactivité croisée (Details): Species reactivity (tested):Human

Purification: Protein A column followed by peptide affinity purification

Immunogène: KLH conjugated synthetic peptide between 206~236 amino acids from the Central region of human TLE1

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.

Détails sur TLE1

Antigène: TLE1 (Transducin-Like Enhancer of Split 1 (E(sp1) Homolog, Drosophila) (TLE1))

Autre désignation: TLE1 (TLE1 Produits)

Synonymes: anticorps ESG, anticorps ESG1, anticorps GRG1, anticorps C230057C06Rik, anticorps Estm14, anticorps Grg1, anticorps Tle4l, anticorps TLE1, anticorps transducin like enhancer of split 1, anticorps transducin-like enhancer protein 1, anticorps transducin-like enhancer of split 1, anticorps transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila), anticorps TLE1, anticorps Smp_150080, anticorps Tle1, anticorps LOC100354911, anticorps LOC100524475, anticorps LOC100061341

Sujet: Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG.Synonyms: ESG1, Enhancer of split groucho-like protein 1, Transducin-like enhancer protein 1

ID gène: 7088

NCBI Accession: NP_005068

Pathways: Signalisation WNT, SARS-CoV-2 Protein Interactome