FGF1 anticorps (C-Term)

N° du produit ABIN966136

Détail du produit anti-FGF1 anticorps

Antigène: FGF1 (Fibroblast Growth Factor 1 (Acidic) (FGF1))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Veuillez nous consulter SVP

Clonalité: Polyclonal

Conjugué: Cet anticorp FGF1 est non-conjugé

Application: Western Blotting (WB)

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminal of human FGF1, identical to the related rat and mouse sequence.

Information d'application

Restrictions: For Research Use only

Stockage

Reconstitution: 0.2ml of distilled water will yield a concentration of 500µg/ml.

Buffer: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4

Agent conservateur: Thimerosal (Merthiolate), Sodium azide

Stock: -20 °C

Références pour anticorps anti-FGF1 (ABIN966136)

Le Beau, Espinosa, Neuman, Stock, Roulston, Larson, Keinanen, Westbrook: "Cytogenetic and molecular delineation of the smallest commonly deleted region of chromosome 5 in malignant myeloid diseases." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 90, Issue 12, pp. 5484-8, (1993) (PubMed).

Mergia, Eddy, Abraham, Fiddes, Shows: "The genes for basic and acidic fibroblast growth factors are on different human chromosomes." dans: Biochemical and biophysical research communications, Vol. 138, Issue 2, pp. 644-51, (1986) (PubMed).

Burgess, Mehlman, Marshak, Fraser, Maciag: "Structural evidence that endothelial cell growth factor beta is the precursor of both endothelial cell growth factor alpha and acidic fibroblast growth factor." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 83, Issue 19, pp. 7216-20, (1986) (PubMed).

Détails sur FGF1

Antigène: FGF1 (Fibroblast Growth Factor 1 (Acidic) (FGF1))

Autre désignation: FGF1 (FGF1 Produits)

Synonymes: anticorps AFGF, anticorps ECGF, anticorps ECGF-beta, anticorps ECGFA, anticorps ECGFB, anticorps FGF-1, anticorps FGF-alpha, anticorps FGFA, anticorps GLIO703, anticorps HBGF-1, anticorps HBGF1, anticorps Fgf1, anticorps FGF1, anticorps aFGF, anticorps ecgf, anticorps fgfa, anticorps ecgfa, anticorps ecgfb, anticorps fgf-1, anticorps hbgf1, anticorps glio703, anticorps ecgf-beta, anticorps fgf-alpha, anticorps Dffrx, anticorps Fam, anticorps Fgf-1, anticorps Fgfa, anticorps zgc:136885, anticorps LOC100221393, anticorps fgf1, anticorps zgc:73249, anticorps fibroblast growth factor 1, anticorps fibroblast growth factor 1 L homeolog, anticorps fibroblast growth factor 1b, anticorps fibroblast growth factor 1a, anticorps FGF1, anticorps fgf1.L, anticorps fgf1, anticorps Fgf1, anticorps fgf1b, anticorps LOC100221393, anticorps fgf1a

Sujet: Fibroblast growth factor 1 (acidic), also known as FGF1/ECGF/HBGF1, is a human gene which is mapped to 5q311. The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis. Additionally, Acidic fibroblast growth factor is derived from beta-endothelial cell growth factor (ECGFB) by posttranslational processing. Alpha-ECGF is also derived from ECGFB in the same manner.2, 3

Pathways: Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway