c-MET anticorps

N° du produit ABIN966572

5+ publications sont disponibles pour ce produit. L’anticorps anti-c-MET Polyclonal produit chez le Lapin a été validé pour IHC. Il convient pour la détection de c-MET dans des échantillons provenant de Humain, Souris et Rat. }

Aperçu rapide pour c-MET anticorps (ABIN966572)

Antigène: c-MET (MET) (Met Proto-Oncogene (MET))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp c-MET est non-conjugé

Application: Immunohistochemistry (IHC)

Détail du produit anti-c-MET anticorps

Specificité: Met (Ab-1349) antibody detects endogenous levels of total Met protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: The antiserum was produced against synthesized non-phosphopeptide derived from human Met around the phosphorylation site of tyrosine 1349 (E-H-YP-V-H).

Information d'application

Indications d'application: WB: 1:500~1:1000.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 100ug/100ul.

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Références pour anticorps anti-c-MET (ABIN966572)

Schiering, Knapp, Marconi, Flocco, Cui, Perego, Rusconi, Cristiani: "Crystal structure of the tyrosine kinase domain of the hepatocyte growth factor receptor c-Met and its complex with the microbial alkaloid K-252a." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 22, pp. 12654-9, (2003) (PubMed).

Fan, Ma, Gao, Yuan, Meng, Goldberg, Rosen: "The multisubstrate adapter Gab1 regulates hepatocyte growth factor (scatter factor)-c-Met signaling for cell survival and DNA repair." dans: Molecular and cellular biology, Vol. 21, Issue 15, pp. 4968-84, (2001) (PubMed).

Jackson, Galinha, Pereira, Fortunato, Soares, Amâncio, Pinto Ricardo: "Rapid deposition of extensin during the elicitation of grapevine callus cultures is specifically catalyzed by a 40-kilodalton peroxidase." dans: Plant physiology, Vol. 127, Issue 3, pp. 1065-76, (2001) (PubMed).

Plopper, McNamee, Dike, Bojanowski, Ingber: "Convergence of integrin and growth factor receptor signaling pathways within the focal adhesion complex." dans: Molecular biology of the cell, Vol. 6, Issue 10, pp. 1349-65, (1996) (PubMed).

Ponzetto, Bardelli, Maina, Longati, Panayotou, Dhand, Waterfield, Comoglio: "A novel recognition motif for phosphatidylinositol 3-kinase binding mediates its association with the hepatocyte growth factor/scatter factor receptor." dans: Molecular and cellular biology, Vol. 13, Issue 8, pp. 4600-8, (1993) (PubMed).

Détails sur c-MET

Antigène: c-MET (MET) (Met Proto-Oncogene (MET))

Autre désignation: Met

Pathways: Signalisation RTK, Carbohydrate Homeostasis, Synaptic Membrane, Signaling of Hepatocyte Growth Factor Receptor