TGFA anticorps (C-Term)

N° du produit ABIN967168

Détail du produit anti-TGFA anticorps

Antigène: TGFA (Transforming Growth Factor, alpha (TGFA))

Épitope: AA 73-90, C-Term

Reactivité: Humain

Hôte: Veuillez nous consulter SVP

Clonalité: Polyclonal

Conjugué: Cet anticorp TGFA est non-conjugé

Application: Western Blotting (WB)

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminal of human TGF (73-90 aa), different from the mouse sequence by one amino acid.

Information d'application

Restrictions: For Research Use only

Stockage

Reconstitution: 0.2ml of distilled water will yield a concentration of 500µg/ml.

Buffer: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4

Agent conservateur: Thimerosal (Merthiolate), Sodium azide

Stock: -20 °C

Références pour anticorps anti-TGFA (ABIN967168)

Fallon, Reid, Kinyamu, Opole, Opole, Baratta, Korc, Endo, Duong, Nguyen, Karkehabadhi, Twardzik, Patel, Loughlin: "In vivo induction of massive proliferation, directed migration, and differentiation of neural cells in the adult mammalian brain." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 97, Issue 26, pp. 14686-91, (2001) (PubMed).

Détails sur TGFA

Antigène: TGFA (Transforming Growth Factor, alpha (TGFA))

Autre désignation: TGFalpha (TGFA Produits)

Synonymes: anticorps TFGA, anticorps LOC100009482, anticorps TGF alpha, anticorps TGFA, anticorps wa-1, anticorps wa1, anticorps RATTGFAA, anticorps TGFAA, anticorps NV15606, anticorps si:ch211-10e8.7, anticorps transforming growth factor alpha, anticorps transforming growth factor alpha L homeolog, anticorps transforming growth factor-alpha, anticorps transforming growth factor, alpha, anticorps TGFA, anticorps TGF-A, anticorps Tgfa, anticorps tgfa.L, anticorps LOC100121300, anticorps LOC100009150, anticorps tgfa

Sujet: Transforming growth factor alpha (TGF-) is upregulated in some human cancers. It is produced in macrophages, brain cells, and keratinocytes, and induces epithelial development. It is closely related to EGF, and can also bind to the EGF receptor with similar effects . TGF stimulates neural cell proliferation in the adult injured brain. TGF was cited in the 2001 NIH Stem Cell report to the U.S. Congress as promising evidence for the ability of adult stem cells to restore function in neurodegenerative disorders.

Pathways: Signalisation NF-kappaB, Signalisation RTK, EGFR Signaling Pathway