Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to very C-terminal residues of mouse Znt6 (Zinc transporter 6) protein
SLC30A6
Reactivité: Humain, Souris
WB, ELISA
Hôte: Lapin
Polyclonal
unconjugated
Restrictions
For Research Use only
Stock
4 °C
Smith, Xiong, Markesbery, Lovell: "Altered expression of zinc transporters-4 and -6 in mild cognitive impairment, early and late Alzheimer's disease brain." dans: Neuroscience, Vol. 140, Issue 3, pp. 879-88, (2006) (PubMed).
Seve, Chimienti, Devergnas, Favier: "In silico identification and expression of SLC30 family genes: an expressed sequence tag data mining strategy for the characterization of zinc transporters' tissue expression." dans: BMC genomics, Vol. 5, Issue 1, pp. 32, (2004) (PubMed).
Huang, Kirschke, Gitschier: "Functional characterization of a novel mammalian zinc transporter, ZnT6." dans: The Journal of biological chemistry, Vol. 277, Issue 29, pp. 26389-95, (2002) (PubMed).
Antigène
SLC30A6
(Solute Carrier Family 30 (Zinc Transporter), Member 6 (SLC30A6))
anticorps MST103, anticorps MSTP103, anticorps ZNT6, anticorps 9530029F08Rik, anticorps ZnT6, anticorps solute carrier family 30 member 6, anticorps solute carrier family 30 (zinc transporter), member 6, anticorps Slc30a6, anticorps SLC30A6
Sujet
Znt6 (Zinc transporter 6) functions Zinc-efflux transporter which allocates the cytoplasmic zinc to the trans-Golgi network (TGN) as well as the vesicular compartment. Znt6 interacts with ZNT5. Znt6 is localized in Golgi apparatus, trans-Golgi network membrane, It is a multi-pass membrane protein and is expressed in brain and liver, and to a lower extent also in lung. Znt6 seems to have lost most of the histidine residues in the loop between the fourth and fifth transmembrane regions and appears to exert transport function by forming complexes with ZNT5. Znt6 belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family and SLC30A subfamily. Synonyms: Slc30a6 (Solute carrier family 30 member 6)