GSK3 alpha anticorps
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- Antigène Voir toutes GSK3 alpha (GSK3a) Anticorps
- GSK3 alpha (GSK3a) (Glycogen Synthase Kinase 3 alpha (GSK3a))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp GSK3 alpha est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- Purification
- purified
- Immunogène
- Purified recombinant fragment of GSK3 alpha expressed in E. coli.
- Clone
- 6G2F1
- Top Product
- Discover our top product GSK3a Anticorps primaire
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- Indications d'application
- ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- 4°C, -20°C for long term storage
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GSK-3 is activated by the tyrosine kinase Pyk2 during LPA1-mediated neurite retraction." dans: Molecular biology of the cell, Vol. 17, Issue 4, pp. 1834-44, (2006) (PubMed).
: "Cyclic ADP-ribose increases Ca2+ removal in smooth muscle." dans: Journal of cell science, Vol. 116, Issue Pt 21, pp. 4291-306, (2003) (PubMed).
: "GSK-3: tricks of the trade for a multi-tasking kinase." dans: Journal of cell science, Vol. 116, Issue Pt 7, pp. 1175-86, (2003) (PubMed).
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GSK-3 is activated by the tyrosine kinase Pyk2 during LPA1-mediated neurite retraction." dans: Molecular biology of the cell, Vol. 17, Issue 4, pp. 1834-44, (2006) (PubMed).
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- Antigène
- GSK3 alpha (GSK3a) (Glycogen Synthase Kinase 3 alpha (GSK3a))
- Autre désignation
- GSK3 alpha (GSK3a Produits)
- Synonymes
- anticorps 2700086H06Rik, anticorps GSK3A, anticorps GSK-3[a], anticorps GSK-3[b], anticorps GSK3, anticorps gsk3a, anticorps xgsk3, anticorps glycogen synthase kinase 3 alpha, anticorps glycogen synthase kinase 3 alpha b, anticorps glycogen synthase kinase 3 alpha S homeolog, anticorps GSK3A, anticorps Gsk3a, anticorps gsk3a, anticorps gsk3ab, anticorps gsk3a.S, anticorps Bm1_31380
- Sujet
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Description: GSK3 alpha (Glycogen synthase kinase 3 alpha), with 483-amino acid protein (about 53 kDa), belongs to the Ser/Thr family of protein kinases, Cdc2/cdkx subfamily,GSK3 subsubfamily, which also includes GSK3 beta.GSK3 is a multifunctional serine/threonine kinase that is usually inactivated by serine phosphorylation in response to extracellular cues. GSK3 is a key regulator of numerous signalling pathways, including cellular responses to Wnt, receptor tyrosine kinases and G-protein-coupled receptors and is involved in a wide range of cellular processes, ranging from glycogen metabolism to cell cycle regulation and proliferation.GSK3 alpha is implicated in the control of several regulatory proteins including glycogen synthase and transcription factors.
Aliases: DKFZp686D0638, GSK3A
- ID gène
- 2931
- HGNC
- 2931
- Pathways
- Signalisation PI3K-Akt, Signalisation WNT, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, cAMP Metabolic Process, Cellular Glucan Metabolic Process, Regulation of Muscle Cell Differentiation, Regulation of G-Protein Coupled Receptor Protein Signaling, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, BCR Signaling, L'effet Warburg
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