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SNCG (Breast Cancer-Specific Protein 1) anticorps

Reactivité: Humain IHC, ELISA, WB Hôte: Souris Monoclonal 1H10D2 unconjugated
N° du produit ABIN969490
  • Antigène
    SNCG (Breast Cancer-Specific Protein 1)
    Reactivité
    Humain
    Hôte
    Souris
    Clonalité
    • 1
    Monoclonal
    Conjugué
    • 1
    Inconjugué
    Application
    Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
    Purification
    purified
    Immunogène
    Purified recombinant fragment of SNCG expressed in E. coli.
    Clone
    1H10D2
    Isotype
    IgG1
  • Indications d'application
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS containing 0.03 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    4°C, -20°C for long term storage
  • Surgucheva, McMahon, Surguchov: "gamma-synuclein has a dynamic intracellular localization." dans: Cell motility and the cytoskeleton, Vol. 63, Issue 8, pp. 447-58, (2006) (PubMed).

    Brown, Lasek: "Polylysine cross-links axoplasmic neurofilaments into tight bundles." dans: Cell motility and the cytoskeleton, Vol. 31, Issue 1, pp. 9-21, (1995) (PubMed).

  • Antigène
    SNCG (Breast Cancer-Specific Protein 1)
    Sujet

    Description: SNCG(also designated gamma-synuclein or breast cancer-specific protein 1),with 127-amino acid protein(about 14 kDa), belongs to the synuclein family, which also includes alpha- and beta- synuclein.Three synucleins are located in the neuronal cytosol and enriched in presynaptic terminals,while SNCG is also expressed in many other non-neuronal tissues. SNCG is abnormally expressed in a high percentage of tumor tissues of diversified cancer types, including liver, esophagus, colon, gastric, lung, prostate, cervical, and breast cancer, but rarely expressed in tumor-matched nonneoplastic adjacent tissues. High levels of SNCG have been identified in advanced breast carcinomas suggesting a correlation between overexpression of SNCG and breast tumor development.

    Aliases: SR, BCSG1

    ID gène
    6623
    HGNC
    6623
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