SNCG (Breast Cancer-Specific Protein 1) anticorps
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- Antigène
- SNCG (Breast Cancer-Specific Protein 1)
- Reactivité
- Humain
- Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Inconjugué
- Application
- Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
- Purification
- purified
- Immunogène
- Purified recombinant fragment of SNCG expressed in E. coli.
- Clone
- 1H10D2
- Isotype
- IgG1
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- Indications d'application
- ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS containing 0.03 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- 4°C, -20°C for long term storage
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gamma-synuclein has a dynamic intracellular localization." dans: Cell motility and the cytoskeleton, Vol. 63, Issue 8, pp. 447-58, (2006) (PubMed).
: "Polylysine cross-links axoplasmic neurofilaments into tight bundles." dans: Cell motility and the cytoskeleton, Vol. 31, Issue 1, pp. 9-21, (1995) (PubMed).
: "
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gamma-synuclein has a dynamic intracellular localization." dans: Cell motility and the cytoskeleton, Vol. 63, Issue 8, pp. 447-58, (2006) (PubMed).
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- Antigène
- SNCG (Breast Cancer-Specific Protein 1)
- Sujet
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Description: SNCG(also designated gamma-synuclein or breast cancer-specific protein 1),with 127-amino acid protein(about 14 kDa), belongs to the synuclein family, which also includes alpha- and beta- synuclein.Three synucleins are located in the neuronal cytosol and enriched in presynaptic terminals,while SNCG is also expressed in many other non-neuronal tissues. SNCG is abnormally expressed in a high percentage of tumor tissues of diversified cancer types, including liver, esophagus, colon, gastric, lung, prostate, cervical, and breast cancer, but rarely expressed in tumor-matched nonneoplastic adjacent tissues. High levels of SNCG have been identified in advanced breast carcinomas suggesting a correlation between overexpression of SNCG and breast tumor development.
Aliases: SR, BCSG1
- ID gène
- 6623
- HGNC
- 6623
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