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Human Monoclonal CCR2 Primary Antibody pour FACS - ABIN4895496
Tsujioka, Imanishi, Ikejima, Kuroi, Takarada, Tanimoto, Kitabata, Okochi, Arita, Ishibashi, Komukai, Kataiwa, Nakamura, Hirata, Tanaka, Akasaka: Impact of heterogeneity of human peripheral blood monocyte subsets on myocardial salvage in patients with primary acute myocardial infarction. dans Journal of the American College of Cardiology 2009
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Human Monoclonal CCR2 Primary Antibody pour CyTOF, FACS - ABIN4899089
Manley, Caso, Works, Cutler, Zemlyak, Sun, Munhoz, Chang, Sorrells, Ermini, Decker, Bertrand, Dinkel, Steinberg, Sapolsky: Derivation of injury-responsive dendritic cells for acute brain targeting and therapeutic protein delivery in the stroke-injured rat. dans PLoS ONE 2013
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Mouse (Murine) Monoclonal CCR2 Primary Antibody pour FACS - ABIN4898202
Benencia, Harshman, Duran-Ortiz, Lubbers, List, Householder, Al-Naeeli, Liang, Welch, Kopchick, Berryman: Male bovine GH transgenic mice have decreased adiposity with an adipose depot-specific increase in immune cell populations. dans Endocrinology 2015
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Mouse (Murine) Monoclonal CCR2 Primary Antibody pour FACS - ABIN4898196
Mikami, Sueda, Ogitani, Otani, Takatsuji, Wada, Watanabe, Yoshikawa, Nishioka, Hashimoto, Miyagi, Fukada, Yamamoto, Tsujikawa: Calcitonin gene-related peptide regulates type IV hypersensitivity through dendritic cell functions. dans PLoS ONE 2014
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Human Monoclonal CCR2 Primary Antibody pour FACS - ABIN4895487
Shantsila, Wrigley, Tapp, Apostolakis, Montoro-Garcia, Drayson, Lip: Immunophenotypic characterization of human monocyte subsets: possible implications for cardiovascular disease pathophysiology. dans Journal of thrombosis and haemostasis : JTH 2011
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Mouse (Murine) Monoclonal CCR2 Primary Antibody pour FACS - ABIN4898198
Levy, Milikovsky, Baranauskas, Vinogradov, David, Ketzef, Abutbul, Weissberg, Kamintsky, Fleidervish, Friedman, Monsonego: Differential TGF-β Signaling in Glial Subsets Underlies IL-6-Mediated Epileptogenesis in Mice. dans Journal of immunology (Baltimore, Md. : 1950) 2015
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Human Monoclonal CCR2 Primary Antibody pour FACS - ABIN4895488
Dagouassat, Suffee, Hlawaty, Haddad, Charni, Laguillier, Vassy, Martin, Schischmanoff, Gattegno, Oudar, Sutton, Charnaux: Monocyte chemoattractant protein-1 (MCP-1)/CCL2 secreted by hepatic myofibroblasts promotes migration and invasion of human hepatoma cells. dans International journal of cancer 2010
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Human Polyclonal CCR2 Primary Antibody pour FACS, ICC - ABIN4288963
Carlson, Helterline, Asbe, Dupras, Minami, Farris, Stempien-Otero: Cardiac macrophages adopt profibrotic/M2 phenotype in infarcted hearts: Role of urokinase plasminogen activator. dans Journal of molecular and cellular cardiology 2016
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Human Polyclonal CCR2 Primary Antibody pour FACS, ICC - ABIN4288961
Sakumoto, Hayashi, Fujii, Kanahara, Hosoe, Furusawa, Kizaki: Possible Roles of CC- and CXC-Chemokines in Regulating Bovine Endometrial Function during Early Pregnancy. dans International journal of molecular sciences 2017
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Human Polyclonal CCR2 Primary Antibody pour ELISA, IP - ABIN4288972
Segerer: The role of chemokines and chemokine receptors in progressive renal diseases. dans American journal of kidney diseases : the official journal of the National Kidney Foundation 2003
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CCR2 polymorphism rs1799864A is associated with Japanese encephalitis virus (JEV) infection in Indian population.
The expression of CCR2 on monocytes could be important for the degree of arterial wall inflammation in atherosclerosis, thereby mediating cardiovascular event risk.
The CCR2 rs1799864 polymorphism was associated with lower International Prostate Symptom Score values and low Qmax in benign prostatic hyperplasia Chinese patients.
CCR2 levels were remarkably up-regulated in calcified aortic valve and calcifying primary aortic valvular interstitial cells (AVICs). Silencing CCR2 inhibited the osteoblastic transformation and calcification of AVICs.
Higher expression of CCL7 receptor CCR2 (C-C chemokine receptor type 2) was associated with shorter overall survival of colorectal cancer patients.
CD11c(+)CD206(+) myeloid cells, previously associated with human adipose tissue inflammation, infiltrate into liver tissue in nonalcoholic fatty liver disease. These cells express CCR2.
We found that CCR2B is upregulated in the EpsteinBarr virus-positive Burkitt Lymphoma cells with latency III.
Results show a reduced expression of CCR2 in Treg cells isolated from pancreas draining lymph nodes of patients with T1D. Also, CCR2 3'UTR was found to be directly targeted by mir-125a.
These findings support the hypothesis that CCR2-CCR5 genes and their haplotypes are associated with chronic Chagas cardiomyopathy; however, depending on the population studied, different associations can be found.
Prognostic significance of monocyte chemoattractant protein-1 and CC chemokine receptor 2 in diffuse large B cell lymphoma.
Results demonstrate that CCR2 overexpression in ductal carcinoma in situ (DCIS) lesions enhances invasive progression associated with accumulation of CCL2-expressing fibroblasts.
miR-135a-3p serves as a tumour suppressor gene in ovarian cancer by regulating CCR2.
this study shows that CCR2 is upregulated on peripheral T cells in osteoarthritis
The A allele of CCR2 rs1799864 was associated with a higher MCP-1 level in AD and MCI patients.
Study results revealed that CCR2 promotes epithelialtomesenchymal transition through MMP2 in liver cancer.
NOX4 is induced in early alcoholic liver injury and regulates CCR2/CCL2 mRNA stability thereby promoting recruitment of inflammatory cells and production of proinflammatory cytokines.
T cell-stimulated CLL cells actively recruited monocytes; recruitment critically depended on the C-C-motif-chemokine-receptor-2 axis.
Study found that the activation of CCR2 by its ligand CCL2 increased the expression of SMO and Gli-1, resulting in Hh pathway activation, epithelial-mesenchymal transition and hepatocellular carcinoma cell invasion.
results confirmed that the CCR2 3'UTR acts as a metastasis suppressor by acting as a ceRNA for STARD13 and thus inhibiting RhoA-ROCK1-MLC-F-actin pathway in breast cancer cells.
It can be concluded that MCP-1 and CCR2 polymorphisms are not associated with AgP in Turkish population.
TRPV1 and the MCP-1/CCR2 axis modulate post-urinary tract infections chronic pain.
these results indicate that CCR2+ cells play a primary role in F4/80+ cells migration along healing in intramembranous bones, but its deficiency does not critically impact healing outcome.
CCR2-dependent monocytes/macrophages are a double-edged sword; they worsen acute brain injury, but are essential for neurological recovery by promoting anti-inflammatory macrophage polarization.
the present study highlights a unique and novel function of CCR2 signaling in the regulation of thymic egress.
this study shows that CCR2 mediates increased susceptibility to post-H1N1 bacterial pneumonia by limiting dendritic cell induction of IL-17
these data show a novel role for CCR2 in protective immunity against clinically relevant Mycobacterium tuberculosis infections
The application of the combined siRNAs of SPARC, CCR2, and SMAD3 genes ameliorated inflammation and fibrosis in bleomycin-induced mice. It systemically reinstated multiple biopathways, probably through controlling on different cell types including fibroblasts, monocytes/macrophages, endothelial cells and others.
the data suggest that CCR2 plays a critical role in the recruitment and inflammatory response following injury, and that wound repair may be therapeutically manipulated through modulation of CCR2.
Sphingosine kinase 1 in hepatic stellate cells in liver fibrosis upregulates CCR2 by downregulation of miR-19b-3p.
CD11c(+)CD206(+) myeloid cells, previously associated with adipose tissue inflammation, infiltrate into liver tissue in nonalcoholic fatty liver disease. These cells express CCR2.
gammadeltaT17 cells constitutively express chemokine receptors CCR6 and CCR2
developmental ethanol exposure caused permanent loss of spinal cord neurons and CCR2 signaling played an important role in ethanol neurotoxicity.
Ccl2-Ccr2 signaling recruits a distinct fetal microchimeric population that rescues delayed maternal wound healing.
itration reduced the potential of CCL2 to stimulate monocyte migration in diffusion gradient chemotaxis assays (p < 0.05). This was consistent with a trend towards reduced affinity of the nitrated chemokine for its cognate receptor CCR2b.
Using the Theiler's virus model of encephalitis in C57BL/6 mice study shows that CCR2 as well as CX3CR1 plays a key role in the accumulation of myeloid cells in the CNS and activation of hippocampal myeloid cells upon infection.
Enhanced bacterial clearance in CCR2(-/-) mice correlated with reduced numbers of IMs in spleens and increased numbers of neutrophils in livers.
Inflammatory CCR2(+) cells that reach the injured kidney at initial stages.
ANG II is up-regulated in serum and heart tissues of mice with EAM and that ANG II significantly drives monocyte/macrophage infiltration through the C-C chemokine receptor 2/5 (CCR2/5) axis.
this study shows that CCR-2/TLR-2 triggered signaling in murine peritoneal macrophages intensifies bacterial (Staphylococcus aureus) killing by reactive oxygen species through TNF-R1
This gene encodes two isoforms of a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The receptors encoded by this gene mediate agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This gene is located in the chemokine receptor gene cluster region. Two alternatively spliced transcript variants are expressed by the gene.
C-C chemokine receptor type 2
, MCP-1 receptor
, monocyte chemoattractant protein 1 receptor
, monocyte chemotactic protein 1 receptor
, C-C CHEMOKINE RECEPTOR TYPE 2 (C-C CKR-2) (CC-CKR-2) (CCR-2) (CCR2) (JE/FIC RECEPTOR) (MCP-1 RECEPTOR)
, C-C CKR-2
, JE/FIC receptor
, MIP-1 alphaR
, chemoattractant protein-1 receptor
, chemokine (C-C) receptor 2
, chemokine receptor CCR2
, chemokine receptor