Aperçu des produits pour anti-PLA2G2D (PLA2G2D) Anticorps

Human phospholipase A2, Group IID (PLA2G2D) interaction partners

1. found to induce PLA2G2D expression in mice and in human monocyte-derived macrophages

2. sPLA(2)-IID is present at the head and midpiece in the human sperm, and its activation seems to be involved in acrosomal exocytosis.

3. phospholipid bilayer permeabilization by the hsPLA2GIID is independent of catalytic activity.

4. The Gly80Ser polymorphism may be associated with the body weight loss seen in chronic obstructive pulmonary disease patients. PLA2G2D-Ser enhances the expression of IL-6 and IL-8 compared with PLA2G2D-Gly.

5. TNF-alpha & IFN-gamma induce gene expression of a novel secretory PLA(2)IIDin human airway epithelial cells. The possibility that it is involved in cytokine-mediated inflammation in the respiratory tract is inferred.

6. The GIID sPLA2 is clustered on human chromosome 1 and is differentially expressed in tissues, suggesting it has unique function.

7. overexpression of human secretory phospholipase A2 group IIA leads to an enhanced delivery of cholesterol from phospholipolysed lipoproteins to the liver

8. These results suggest that sPLA2-IID may be one of the susceptibility genes that contribute to body weight loss in patients with COPD.

9. lipopolysaccharides inhibit interferon gamma-induced gene expression of secretory phospholipase A2 type IID in human monocyte-derived macrophages

10. The distribution pattern of sPLA2S in intact spermatozoa might be an additional parameter for evaluating sperm quality

Mouse (Murine) phospholipase A2, Group IID (PLA2G2D) interaction partners

1. these results underscore a general role of sPLA2-IID as an immunosuppressive sPLA2 that allows the microenvironmental lipid balance toward an anti-inflammatory state, exerting beneficial or detrimental impact depending upon distinct pathophysiological contexts in inflammation and cancer.

2. found to induce PLA2G2D expression in mice and in human monocyte-derived macrophages

3. PLA2G2D in the LNs contributed to mobilization of a pool of polyunsaturated fatty acids.