BAFF Kit ELISA

N° du produit ABIN2745441

Détail du produit BAFF Kit ELISA

Antigène: BAFF (TNFSF13B) (Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B))

Reactivité: Humain

Méthode de détection: Colorimetric

Type de méthode: Sandwich ELISA

Gamme de detection: 15.6-500 pg/mL

Seuil minimal de détection: 15.6 pg/mL

Application: ELISA

Type d'échantillon: Cell Culture Supernatant, Plasma, Serum

Analytical Method: Quantitative

Specificité: Detects human BAFF.

Réactivité croisée: Humain

Aucune reactivité croisée: Souris

Réactivité croisée (Details): Does not detect mouse BAFF.

Sensibilité: 8 pg/mL

Attributs du produit: BAFF, Soluble (human) ELISA Kit (Hypersensitive)

Information d'application

Plaque: Pre-coated

Restrictions: For Research Use only

Stockage

Stock: 4 °C

Stockage commentaire: Short Term Storage: +4°C
Long Term Storage: +4°C

Détail du antigène

Antigène: BAFF (TNFSF13B) (Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B))

Autre désignation: BAFF (TNFSF13B Produits)

Synonymes: BAFF Kit ELISA, BLYS Kit ELISA, CD257 Kit ELISA, DTL Kit ELISA, TALL-1 Kit ELISA, TALL1 Kit ELISA, THANK Kit ELISA, TNFSF20 Kit ELISA, ZTNF4 Kit ELISA, BAFF-R Kit ELISA, BAFFR Kit ELISA, BROMIX Kit ELISA, CD268 Kit ELISA, CVID4 Kit ELISA, prolixin Kit ELISA, TNFSF13B Kit ELISA, RGD1561519 Kit ELISA, RGD1560810 Kit ELISA, BLyS Kit ELISA, D8Ertd387e Kit ELISA, zTNF4 Kit ELISA, 2010006P15Rik Kit ELISA, Baffr Kit ELISA, Bcmd Kit ELISA, Bcmd-1 Kit ELISA, Bcmd1 Kit ELISA, Lvis22 Kit ELISA, zgc:172115 Kit ELISA, TNF superfamily member 13b Kit ELISA, TNF receptor superfamily member 13C Kit ELISA, tumor necrosis factor (ligand) superfamily, member 13b Kit ELISA, tumor necrosis factor receptor superfamily, member 13c Kit ELISA, tumor necrosis factor superfamily member 13b Kit ELISA, TNFSF13B Kit ELISA, TNFRSF13C Kit ELISA, Tnfsf13b Kit ELISA, Tnfrsf13c Kit ELISA, tnfsf13b Kit ELISA

Sujet: BAFF (B cell-activating factor, BLyS, B lymphocyte stimulator, TNFSF13B, TALL-1, CD257), belonging to the TNF family, is a master regulator of peripheral B cell survival, and together with IL-6, promotes Ig class-switching and plasma cell differentiation. BAFF co-stimulates activated T cells. Increased levels of soluble BAFF have been detected in the serum of patients with various autoimmune diseases, such as Sjögren's syndrome, rheumatoid arthritis, multiple sclerosis and systemic lupus erythematosus (SLE). Furthermore, BAFF is found in inflammatory sites in which there is lymphoid neogenesis. BAFF levels are elevated in patients with multiple myeloma and B cell chronic lymphoid leukemia (B-CCL).

UniProt: Q5H8V1

Pathways: Signalisation NF-kappaB, Production of Molecular Mediator of Immune Response