Recommendations are based on data provided indicating:
ELISA Kit Sensitivity
The recommended ELISA Kit will likely detect the antigen better in the approved sample types than the available alternatives.
ELISA Kit Specificity
The recommended ELISA Kit will likely detect the antigen in question with higher specificity in approved samples than the available alternatives.
The results will be likely more reproducible, with high inter- or intra-assay CV and Recovery (for values within the std curve) than the available alternatives.
ELISA Kit Robustness
The recommended assay will likely function better with approved sample types, and will not suffer from undue matrix interference than the available alternatives.
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ANG Antigen Profile
Angiostatin is an angiogenesis inhibitor that blocks neovascularization and growth of experimental primary and metastatic tumors in vivo. Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated by CSPG4. Binds to cells (By similarity).
Alternative names and synonyms associated with ANG
plasminogen (Plg) ELISA Kit
AI649309 ELISA Kit
Pg ELISA Kit
Protein level used designations for ANG
, plasmin heavy chain A
, plasmin light chain B