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Human Polyclonal INHBB Primary Antibody pour ELISA, WB - ABIN561500
Brozzetti, Alimohammadi, Morelli, Minarelli, Hallgren, Giordano, De Bellis, Perniola, Kämpe, Falorni: Autoantibody response against NALP5/MATER in primary ovarian insufficiency and in autoimmune Addison's disease. dans The Journal of clinical endocrinology and metabolism 2015
The present study demonstrated that EGF (Montrer EGF Anticorps) controlled expression of three activin (Montrer Actbeta Anticorps) subunits (inhbaa (Montrer INHBA Anticorps), inhbab and inhbb) in the follicle cells via diverse signaling pathways.
whereas the inhibitory effect of hCG (Montrer CGA Anticorps) on activin betaB expression is likely mediated by PKA-independent pathway(s).
Activin (Montrer Actbeta Anticorps) betaA is involved in promoting ovary and follicle growth, whereas activin betaB may have a tonic role throughout follicle development but becomes critical at the late stage of oocyte maturation and/or ovulation.
point mutation enhances the affinity of Noggin2 to ActivinB, while weakens its affinity to BMP.
Noggin2 protected the developing forebrain from inhibition by Activin B (Montrer Actbeta Anticorps) and XWnt8 (Montrer WNT8A Anticorps) signaling.
A new role for activin B (Montrer Actbeta Anticorps) during gastrulation involves cell cycle arrest in the involuting dorsal axial mesoderm.
Used monoclonal antibody to xenopus laevis Inhbb in ELISA for detection of human Inhbb.
Inflammatory stimuli strongly induce Smad2 (Montrer SMAD2 Anticorps) and Smad5 (Montrer SMAD5 Anticorps) phosphorylation in wild-type mice. None of these Smad (Montrer SMAD1 Anticorps) effectors are activated in mice deficient in activin B (Montrer Actbeta Anticorps). Activin B (Montrer Actbeta Anticorps), whose messenger RNA expression is strongly induced after LPS (Montrer TLR4 Anticorps) administration or E coli infection, is required for activation of Smad1 (Montrer SMAD1 Anticorps)/5/8 signaling. Hepcidin (Montrer HAMP Anticorps) expression did not depend on activin B (Montrer Actbeta Anticorps) expression.
These results suggest that prolonged exposure to hyperglycemia in the Ins2(Akita+/-) mice leads to progressive testicular disruption mediated by testicular activin (Montrer Actbeta Anticorps) activity, rather than hormonal dysregulation.
This study tested the hypothesis that inhibins act in an autocrine manner on Leydig cells using a pre-pubertal Leydig cell line, TM3 (Montrer TPM1 Anticorps), as a model of immature Leydig cells.
Menin binds on the promoter of Inhbb gene where it favours the recruitment of Ezh2 (Montrer EZH2 Anticorps) via an indirect mechanism involving Akt (Montrer AKT1 Anticorps)-phosphorylation.
Data suggest Inhbb is physiologically essential for early folliculogenesis; Inhbb appears to participate in regulation of cell cycle progression, apoptosis, and steroidogenesis (estradiol/progesterone synthesis) in ovarian granulosa cells in culture.
Activin B (Montrer Actbeta Anticorps), a transforming growth factor beta - related ligand, is upregulated during tumorigenesis and drives the loss of insulin (Montrer INS Anticorps) expression and beta-cell maturity in a mouse insulinoma (Montrer RPS15 Anticorps) model.
in mammalian spinal cord, Tgfbeta (Montrer TGFB1 Anticorps) ligands and ActB (Montrer ACTB Anticorps) together support oligodendrocyte development and myelin formation
No differences were observed in fasting glucose/insulin (Montrer INS Anticorps) levels, glucose tolerance, insulin (Montrer INS Anticorps) sensitivity, or insulin (Montrer INS Anticorps) secretion in comparing young or older males on in comparing insulin (Montrer INS Anticorps) secretion from islets of wild type or activin B (Montrer Actbeta Anticorps) knockout males.
There is a dramatic induction of Inhbb mRNA, e (Montrer HAMP Anticorps)ncoding the activin beta(B)-subunit, in liver challenged with lipopolysaccharide, slight (Montrer Actbeta Anticorps)ly preceding an increase in Smad1/5/8 phosphorylation and Hamp m (Montrer HAMP Anticorps)RNA.
the transition between stem cells and committed progenitors is neither sharp nor irreversible and GDF11 (Montrer GDF11 Anticorps), ACTbetaB and FST (Montrer FST Anticorps) are crucial components of a circuit that controls both total cell number and the ratio of neuronal versus glial cells in this system
Presence of varicocele was associated with lower serum inhibin B.
Elevated activin B (Montrer Actbeta Anticorps) levels together with normal activin A (Montrer INHBA Anticorps) levels identified patients with the diagnostic symptoms of chronic fatigue syndrome/myalgic encephalomyelitis.
Results identified Inhbb as one factor mediating the proliferative effect of Pdx-1 (Montrer PDX1 Anticorps) on islet cells.
Low activin B (Montrer Actbeta Anticorps) level is associated with tubal ectopic pregnancy.
The Sertoli cell hormones inhibin-B and anti Mullerian hormone (Montrer AMH Anticorps) have different patterns of secretion in prepubertal cryptorchid boys.
Pregnant Han Chinese women carrying the rs7579169 CC genotype and G-G-C haplotype are significantly more likely to develop pre-eclampsia, especially late-onset and multiparous cases.
We report here an original observation that activin-B (Montrer Actbeta Anticorps) is upregulated in the human idiopathic pulmonary fibrosis lung.
reduction of RhoA (Montrer RHOA Anticorps) signaling by Activin B (Montrer Actbeta Anticorps) together with persistent Rac1 activity is a prerequisite for inducing an invasive phenotype in clear cell renal cell carcinoma (Montrer MOK Anticorps).
inhibin B and anti-Mullerian hormone (Montrer AMH Anticorps) serum concentrations did not provide an additional diagnostic tool for male infertility
Activin-A (Montrer INHBA Anticorps) and -B are abundantly expressed in mesothelioma tumor tissue.
An increased expression of Inhibin-beta B was found in oocytes collected from large and medium follicles compared with small follicles before or after in oocyte vitro maturation.
our data indicate that miR (Montrer MYLIP Anticorps)-34a plays an important role in granulosa cell apoptosis by targeting the INHBB gene in the porcine ovary
results indicated that boar testis produces inhibin A and inhibin B during the infantile period but inhibin A is the predominant form towards puberty and molecular weight forms of inhibin and the sites of production change with testicular development
The inhibin beta B subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta B subunit forms a homodimer, activin B, and also joins with the beta A subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion.
activin beta B
, activin B
, activin beta B subunit
, inhibin, beta B
, inhibin beta B
, inhibin, beta B (activin AB beta polypeptide)
, inhibin beta B chain-like
, activin beta-B chain
, activin betaB
, inhibin beta B chain
, inhibin beta subunit B
, Inhibin, beta-2
, activin AB beta polypeptide
, inhibin beta-(b) subunit
, betaB inhibin/activin
, inhibin beta B subunit