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Human Polyclonal DEFB103A Primary Antibody pour ELISA, WB - ABIN2473299
Ulick, Tedde, Mantero: Pathogenesis of the type 2 variant of the syndrome of apparent mineralocorticoid excess. dans The Journal of clinical endocrinology and metabolism 1990
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Human Polyclonal DEFB103A Primary Antibody pour ELISA, WB - ABIN2473300
Harder, Bartels, Christophers, Schroder: Isolation and characterization of human beta -defensin-3, a novel human inducible peptide antibiotic. dans The Journal of biological chemistry 2001
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this study shows that hBD3 amplifies the response to bacterial DNA in both mouse and human immune cells in a TLR9 (Montrer TLR9 Anticorps)-dependent manner
the role of DEFB103 gene copy number variation (CNV) in ankylosing spondylitis (AS) susceptibility, was investigated.
It may be concluded hepatitis B virus up-regulates HBD-3 and A3G expression in vivo and in vitro in placental trophoblast and lack of this up-regulation is possibly associated with intrauterine transmission of hepatitis B.
these observations suggest that there may be an interracial difference in DEFB4 (Montrer DEFB104A Anticorps)/103A copy numbers between admixed populations and a relationship between DEFB1 (Montrer DEFB1 Anticorps) single nucleotide polymorphisms and DEFB4 (Montrer DEFB104A Anticorps)/103A copy number variation
Human beta-defensin 3 peptide is increased and redistributed in Crohn's ileitis
study demonstrates that HBD2 (Montrer DEFB4 Anticorps) and 3 activate plasmacytoid dendritic cells by enhancing the intracellular uptake of CpG and self DNA and promote DNA-induced IFN-alpha (Montrer IFNA Anticorps) production in a TLR9 (Montrer TLR9 Anticorps)-dependent manner
Mapping of key residues in the interaction between human Beta-defensin 3 and CXCR4 (Montrer CXCR4 Anticorps) reveals key defensin (Montrer DEF Anticorps) motifs involved in protein binding.
These results suggest an important role for hBD3 in inducing dendritic cell activation, migration, and polarization.
Using a large, unique cohort of pediatric CA-SAB (Montrer SH3BP5 Anticorps), this study found no significant association between DEFB1 (Montrer DEFB1 Anticorps) genetic variation or DEFB4 (Montrer DEFB104A Anticorps)/DEFB103 gene copy number and susceptibility for Staphylococcus aureus bacteremia
Human beta-defensin 3 exhibits further functions than antimicrobial peptide (Montrer cAMP Anticorps) activity in cultured bone cells, including stimulation of proliferation and differentiation.
Thus, oral epithelial cells dominantly control IL-17R-dependent responses to oropharyngeal candidiasis through regulation of BD3 expression.
C/EBPbeta (Montrer CEBPB Anticorps) contributes to immunity to mucosal candidiasis during cortisone immunosuppression in a manner linked to beta-defensin 3 expression, but is apparently dispensable for the IL-17 (Montrer IL17A Anticorps)-dependent response.
Stress decreases mouse beta-defensin-3 expression in the esophagus of mice with diabetes.
visfatin (Montrer NAMPT Anticorps) enhances CAMP, hBD-2 (Montrer DEFB4 Anticorps), hBD-3, and S100A7 (Montrer S100A7 Anticorps) production in human keratinocytes and their orthologs in murine imiquimod-treated psoriatic skin.
this investigation revealed an indispensable role for BD3, BD4 (Montrer DEFB4 Anticorps), and CRAMP in defense against F. solani-induced keratitis
SP-A (Montrer SFTPA1 Anticorps) protects lung epithelium from tissue injury caused by BD3
Mouse beta-defensin 3 was strongly up-regulated in colonic epithelium of 15 (but not 5) week-old IL-2 (Montrer IL2 Anticorps)(-/-) mice and in dextran-sulfate-induced chronic (but not acute) colitis, but not in IL-2 (Montrer IL2 Anticorps)(+/-) 15-week-old mice.
Epithelial and mucosal tissues expressed bd3 and recombinant bd3 exhibits antifungal activity.
Murine beta-defensins BD2 (Montrer DEFB4 Anticorps) and BD3 together promote resistance against corneal infection by Pseudomonas aeruginosa.
Mycobacterial infection induces the expression of mBD3 (Montrer MBD3 Anticorps) and mBD4 (Montrer MBD4 Anticorps), and both might participate in the control of mycobacterial growth.
Bovine DEFB3 gene expression is upregulated by vitamin D and toll (Montrer TLR4 Anticorps)-like receptor signaling.
The synthetic peptides bovine enteric beta-defensin (EBD (Montrer DEFB1 Anticorps)), bovine neutrophil beta-defensin (Montrer DEFB1 Anticorps) (BNBD) 9 and BNBD 3 are chemotactic for immature dendritic cells.
Beta-defensin (Montrer DEFB1 Anticorps) antimicrobial peptides DEFB2 (Montrer DEFB4 Anticorps) and DEFB3.
Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 103B, which has broad spectrum antimicrobial activity and may play an important role in innate epithelial defense.
, beta-defensin 3
, defensin, beta 103
, defensin, beta 3
, defensin-like protein
, beta defensin 3
, beta-defensin 103A
, defensin, beta 103B
, defensin, beta 103A
, beta-defensin 405
, beta-defensin 6
, bovine neutrophil beta-defensin 3