IKZF1 Kits ELISA
6 IKAROS Family Zinc Finger 1 (Ikaros) (IKZF1) Kits ELISA de 5 fabricants sont disponibles sur www.anticorps-enligne.fr.
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IKZF1 Kit ELISA (IKAROS Family Zinc Finger 1 (Ikaros)) Kit ELISA
IKZF1 Kit ELISA (IKAROS Family Zinc Finger 1 (Ikaros)) Kit ELISA
IKZF1 Kit ELISA (IKAROS Family Zinc Finger 1 (Ikaros)) Kit ELISA
IKZF1 Kit ELISA (IKAROS Family Zinc Finger 1 (Ikaros)) Kit ELISA
IKZF1 Kit ELISA (IKAROS Family Zinc Finger 1 (Ikaros)) Kit ELISA
IKZF1 Kit ELISA (IKAROS Family Zinc Finger 1 (Ikaros)) Kit ELISA
IKZF1 profil antigène
Profil protéine
This gene encodes a transcription factor that belongs to the family of zinc-finger DNA binding proteins associated with chromatin remodeling. The expression of this protein is restricted to the fetal and adult hemo-lymphopoietic system, and it functions as a regulator of lymphocyte differentiation. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. All isoforms share a common C-terminal domain, which contains two zinc finger motifs that are required for hetero- or homodimerization, and for interactions with other proteins. The isoforms, however, differ in the number of N-terminal zinc finger motifs that bind DNA and contain the nuclear localization signal, resulting in members with and without DNA-binding properties. Only few isoforms contain the requisite three or more N-terminal zinc motifs that confer high affinity binding to a specific core DNA sequence element in the promoters of target genes. The non-DNA-binding isoforms are largely found in the cytoplasm, and thought to function as dominant negative factors. Overexpression of some dominant-negative isoforms have been associated with B-cell malignancies, such as acute lymphoblastic leukemia (ALL).
Alternative names and synonyms associated with IKZF1
- IKAROS family zinc finger 1 (IKZF1) anticorps
- IKAROS family zinc finger 1 (Ikzf1) anticorps
- IKAROS family zinc finger 1 (Ikaros) (ikzf1) anticorps
- IKAROS family zinc finger 1 (ikzf1) anticorps
- 5832432G11Rik anticorps
- hik-1 anticorps
- hlk-1 anticorps
- hs.54452 anticorps
- ik1 anticorps
- Ikaros anticorps
- ikzf1 anticorps
- LyF-1 anticorps
- lyf1 anticorps
- MGC108252 anticorps
- mKIAA4227 anticorps
- pro0758 anticorps
- RGD1562979 anticorps
- Zfpn1a1 anticorps
- Znfn1a1 anticorps
Protein level used designations for IKZF1
CLL-associated antigen KW-6 , DNA-binding protein Ikaros , Ikaros (zinc finger protein) , ikaros family zinc finger protein 1 , lymphoid transcription factor LyF-1 , zinc finger protein, subfamily 1A, 1 (Ikaros) , Ikaros transcription factor , KAROS family zinc finger 1 (Ikaros) , IKAROS family zinc finger 1 (Ikaros) , DNA-binding protein Ikaros-like , zinc finger protein subfamily 1A, 1
GENE ID | SPECIES |
---|---|
10320 | Homo sapiens |
305501 | Rattus norvegicus |
30177 | Danio rerio |
395974 | Gallus gallus |
483231 | Canis lupus familiaris |
541154 | Bos taurus |
548415 | Xenopus (Silurana) tropicalis |
744299 | Pan troglodytes |
100052437 | Equus caballus |
100356499 | Oryctolagus cuniculus |
100380614 | Salmo salar |
100403568 | Callithrix jacchus |
100436638 | Pongo abelii |
100475874 | Ailuropoda melanoleuca |
100601106 | Nomascus leucogenys |
22778 | Mus musculus |
100136762 | Oncorhynchus mykiss |
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