Osteoactivin Protein (GPNMB) (AA 22-486) (His tag)

N° du produit ABIN1097263

Détail du produit

Antigène: Osteoactivin (GPNMB)

Type de proteíne: Recombinant

Attributs du protein: AA 22-486

Origine: Humain

Source: Human Cells

Purification/Conjugué: Cette Osteoactivin protéine est marqué à la His tag.

Fonction: Recombinant Human Osteoactivin/GPNMB (C-6His)

Séquence: AKRFHDVLGN ERPSAYMREH NQLNGWSSDE NDWNEKLYPV WKRGDMRWKN SWKGGRVQAV LTSDSPALVG SNITFAVNLI FPRCQKEDAN GNIVYEKNCR NEAGLSADPY VYNWTAWSED SDGENGTGQS HHNVFPDGKP FPHHPGWRRW NFIYVFHTLG QYFQKLGRCS VRVSVNTANV TLGPQLMEVT VYRRHGRAYV PIAQVKDVYV VTDQIPVFVT MFQKNDRNSS DETFLKDLPI MFDVLIHDPS HFLNYSTINY KWSFGDNTGL FVSTNHTVNH TYVLNGTFSL NLTVKAAAPG PCPPPPPPPR PSKPTPSLAT TLKSYDSNTP GPAGDNPLEL SRIPDENCQI NRYGHFQATI TIVEGILEVN IIQMTDVLMP VPWPESSLID FVVTCQGSIP TEVCTIISDP TCEITQNTVC SPVDVDEMCL LTVRRTFNGS GTYCVNLTLG DDTSLALTST LISVPVDHHH HHH

Attributs du produit: Recombinant Human Transmembrane Glycoprotein NMB/GPNMB produced by transfected human cells is a secreted protein with sequence (Ala22-Pro486) of Human GPNMB fused with a polyhistidine tag at the C-terminus.

Pureté: > 95 % as determined by reducing SDS-PAGE.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.

Conseil sur la manipulation: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Stock: 4 °C/-20 °C/-80 °C

Stockage commentaire: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Date de péremption: 3 months

Détail du antigène

Antigène: Osteoactivin (GPNMB)

Autre désignation: gpnmb (GPNMB Produits)

Synonymes: HGFIN Protein, NMB Protein, DC-HIL Protein, Dchil Protein, ipd Protein, glycoprotein nmb Protein, glycoprotein (transmembrane) nmb Protein, glycoprotein nmb L homeolog Protein, Gpnmb Protein, GPNMB Protein, gpnmb.L Protein

Sub Type: Fusionprotein

Sujet: Osteoactivin is an intracellular glycoprotein belongs to the NMB/pMEL-17 family, which is asscociated with cell endosomal/lysomal compartments. Human Osteoactivin is a 560 amino acid type I transmembrane protein, and one alternate splice form shows a 12 amino acid insert between amino acid 339-340. An additional 206 amino acid isoform shows a mutation at position 181 that results in a 26 amino acid substitution for the C-terminal 380 amino acids. Cells knowns to express Osteoactivin include fibroblast, osteoblasts, myeloid dendritic cell, melanocytes, plus fetal chondrocytes and stratum basale keratinocytes, macrophages/keratinocytes.
Alternative Names: Transmembrane Glycoprotein NMB, Transmembrane Glycoprotein HGFIN, GPNMB, HGFIN, NMB

Poids moléculaire: 53.09 kDa

UniProt: Q14956