CSK Protein (AA 1-450) (GST tag)

N° du produit ABIN1350517

Cette protéine Recombinant CSK est produite dans Wheat germ. Il y a 1 publication disponible.

Aperçu rapide pour CSK Protein (AA 1-450) (GST tag) (ABIN1350517)

Antigène: CSK (C-Src tyrosine Kinase (CSK))

Type de proteíne: Recombinant

Origine: Humain

Source: Wheat germ

Application: Western Blotting (WB), ELISA, Antibody Array (AA), Affinity Purification (AP)

Détail du produit

Attributs du protein: AA 1-450

Purification/Conjugué: Cette CSK protéine est marqué à la GST tag.

Fonction: CSK (Human) Recombinant Protein (P01)

Séquence: MSAIQAAWPS GTECIAKYNF HGTAEQDLPF CKGDVLTIVA VTKDPNWYKA KNKVGREGII PANYVQKREG VKAGTKLSLM PWFHGKITRE QAERLLYPPE TGLFLVREST NYPGDYTLCV SCDGKVEHYR IMYHASKLSI DEEVYFENLM QLVEHYTSDA DGLCTRLIKP KVMEGTVAAQ DEFYRSGWAL NMKELKLLQT IGKGEFGDVM LGDYRGNKVA VKCIKNDATA QAFLAEASVM TQLRHSNLVQ LLGVIVEEKG GLYIVTEYMA KGSLVDYLRS RGRSVLGGDC LLKFSLDVCE AMEYLEGNNF VHRDLAARNV LVSEDNVAKV SDFGLTKEAS STQDTGKLPV KWTAPEALRE KKFSTKSDVW SFGILLWEIY SFGRVPYPRI PLKDVVPRVE KGYKMDAPDG CPPAVYEVMK NCWHLDAAMR PSFLQLREQL EHIKTHELHL

Attributs du produit: Human CSK full-length ORF ( NP_004374.1, 1 a.a. - 450 a.a.) recombinant protein with GST-tag at N-terminal.

Purification: in vitro wheat germ expression system

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

Preparation method: in vitro, wheat germ expression system
Product Quality tested by: 12.5% SDS-PAGE Stained with Coomassie Blue.

Restrictions: For Research Use only

Stockage

Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH =8.0 in the elution buffer.

Conseil sur la manipulation: Aliquot to avoid repeated freezing and thawing.

Stock: -80 °C

Stockage commentaire: Best use within three months from the date of receipt of this protein.

Référence

Jo, Park, Lee, Ahn, Kim, Park, Choi: "SHP-2 binds to caveolin-1 and regulates Src activity via competitive inhibition of CSK in response to H2O2 in astrocytes." dans: PLoS ONE, Vol. 9, Issue 3, pp. e91582, (2014) (PubMed).

Détail du antigène

Antigène: CSK (C-Src tyrosine Kinase (CSK))

Autre désignation: CSK

Sujet: Full Gene Name: c-src tyrosine kinase
Synonyms: MGC117393

ID gène: 1445

NCBI Accession: NM_004383

Pathways: TCR Signaling, EGFR Signaling Pathway, Cell-Cell Junction Organization, CXCR4-mediated Signaling Events