Glypican 3 Protein (GPC3)
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- Antigène Voir toutes Glypican 3 (GPC3) Protéines
- Glypican 3 (GPC3)
- Type de proteíne
- Recombinant
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Pureté
- > 95 % by SDS-PAGE
- Top Product
- Discover our top product GPC3 Protéine
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Glypican 3 (GPC3) (AA 25-559) protein (His tag)
GPC3 Origine: Humain Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Glypican 3 (GPC3) (AA 25-559) protein (His tag)GPC3 Origine: Cynomolgus Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Glypican 3 (GPC3) (AA 25-559) protein (His-Avi Tag,Biotin)GPC3 Origine: Humain Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Glypican 3 (GPC3) (AA 438-554) (Active) protein-VLPGPC3 Origine: Humain Hôte: HEK-293 Cells VLP > 95 % as determined by HPLC Imm, ELISA, Func, SPR Active
Glypican 3 (GPC3) (AA 25-559) (Active) protein (Fc Tag)GPC3 Origine: Cynomolgus Hôte: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE Func Active
Glypican 3 (GPC3) (AA 25-559) (Active) protein (Fc Tag)GPC3 Origine: Humain Hôte: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE Func Active
Glypican 3 (GPC3) (AA 25-559) (Active) protein (His tag)GPC3 Origine: Humain Hôte: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Glypican 3 (GPC3) (AA 25-559) (Active) protein (His tag,AVI tag,Biotin)GPC3 Origine: Humain Hôte: HEK-293 Cells Recombinant >85 % as determined by SDS-PAGE. Active
Glypican 3 (GPC3) protein (His tag)GPC3 Origine: Souris Hôte: Human Cells Recombinant >95 % as determined by reducing SDS-PAGE.
Glypican 3 (GPC3) (AA 301-400) protein (GST tag)GPC3 Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AA, AP
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- 10 mM Tris-HCL (pH 8.8 +/- 0.2) with 0.05 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
- Stock
- 4 °C
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- Antigène
- Glypican 3 (GPC3)
- Autre désignation
- Glypican-3 (GPC3 Produits)
- Synonymes
- GPC3 Protein, sgb Protein, dgsx Protein, sdys Protein, sgbs Protein, oci-5 Protein, sgbs1 Protein, DGSX Protein, GTR2-2 Protein, MXR7 Protein, OCI-5 Protein, SDYS Protein, SGB Protein, SGBS Protein, SGBS1 Protein, Glypican-3 Protein, glypican 3 Protein, gpc3 Protein, GPC3 Protein, Gpc3 Protein
- Sujet
- Glypican 3, GPC3 is a member of the glypican family that are heparan sulfate proteoglycans that bind to the exocytoplasmic surface of the plasma membrane through a covalent glycosylphosphatidylinositol (GPI) linkage. GPC3 gene contains 8 exons and encompasses approximately 500 kb. It encodes a putative extracellular proteoglycan, glypican 3, that is inferred to play an important role in growth control in embryonic mesodermal tissues in which it is selectively expressed. GPC3 acts as a negative regulator of Hedgehog signaling during mammalian development and that the overgrowth observed in SGBS (Simpson-Golabi-Behmel overgrowth syndrome) patients is, at least in part, the consequence of hyperactivation of the Hedgehog signaling pathway.
- Pathways
- Glycosaminoglycan Metabolic Process
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