IL1RN Protein (AA 26-177)
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- Antigène Voir toutes IL1RN Protéines
- IL1RN (Interleukin 1 Receptor Antagonist (IL1RN))
- Type de proteíne
- Recombinant
- Activité biologique
- Active
- Attributs du protein
- AA 26-177
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Origine
- Humain
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Source
- HEK-293T Cells
- Attributs du produit
- ED50 < 0.1 μg /mL, measured in a neutralization assay using D10S cells in the presence of 50pg/mL Human IL-1a.
- Pureté
- > 95 % as analyzed by SDS-PAGE and HPLC.
- niveau d'endotoxine
- < 0.2 EU/μg, determined by LAL method.
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- Discover our top product IL1RN Protéine
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Interleukin 1 Receptor Antagonist (IL1RN) (AA 1-159) protein (GST tag)
IL1RN Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AA, AP
Interleukin 1 Receptor Antagonist (IL1RN) (AA 25-178) protein (His tag)IL1RN Origine: Souris Hôte: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Interleukin 1 Receptor Antagonist (IL1RN) protein (Fc Tag)IL1RN Origine: Humain Hôte: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Interleukin 1 Receptor Antagonist (IL1RN) proteinIL1RN Origine: Souris Hôte: Escherichia coli (E. coli) Recombinant > 95 % as determined by SDS-PAGE
Interleukin 1 Receptor Antagonist (IL1RN) (AA 27-178) protein (His tag)Crystallography grade IL1RN Origine: Souris Hôte: Cellules d'insectes Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstituted in ddH2O or PBS at 100 μg/mL.
- Buffer
- Lyophilized after extensive dialysis against PBS.
- Stock
- -80 °C
- Stockage commentaire
- Lyophilized recombinant human IL-1 Receptor Antagonist remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, Human IL-1 Receptor Antagonist should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
- Date de péremption
- 6 months
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- Antigène
- IL1RN (Interleukin 1 Receptor Antagonist (IL1RN))
- Autre désignation
- IL-1 Receptor Antagonist (IL1RN Produits)
- Synonymes
- DIRA Protein, ICIL-1RA Protein, IL-1RN Protein, IL-1ra Protein, IL-1ra3 Protein, IL1F3 Protein, IL1RA Protein, IRAP Protein, MVCD4 Protein, IRAP1 Protein, IL1RN Protein, IL-1RA Protein, F630041P17Rik Protein, interleukin 1 receptor antagonist Protein, interleukin 1 receptor antagonist-like Protein, IL1RN Protein, Il1rn Protein, IL1RNL Protein
- Sujet
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IL-1 Receptor Antagonist, also known as IL-1RA, ICIL-1RA, IRAP and IL-1RN, is a member of the interleukin 1 cytokine family. It is expressed by monocytes, neutrophils, macrophages, epithelial cells and fibroblasts. IL-1RA inhibits the activity of both IL-1alpha and IL-1beta, and modulates a variety of IL-1 related immune and inflammatory responses. It inhibits the activity of IL-1 by binding to the receptor IL-1R1 and preventing its association with the coreceptor IL-1RAP for signaling. Clinical studies are being conducted to investigate the use of IL-1RA in the treatment of sepsis, rheumatoid arthritis and chronic myelogenous leukemia.
Synonyms: IL-1RA, ICIL-1RA, IRAP, IL-1RN - Poids moléculaire
- 18-23 kDa, observed by reducing SDS-PAGE.
- UniProt
- P18510
- Pathways
- Signalisation NF-kappaB, Hormone Transport, Cancer Immune Checkpoints
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