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CD27 Protein (AA 21-192) (Fc Tag)

CD27 Origine: Humain Hôte: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
N° du produit ABIN2180735
  • Antigène Voir toutes CD27 Protéines
    CD27 (CD27 Molecule (CD27))
    Type de proteíne
    Recombinant
    Activité biologique
    Active
    Attributs du protein
    AA 21-192
    Origine
    • 23
    • 11
    • 3
    • 3
    • 1
    Humain
    Source
    • 18
    • 6
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    Purification/Conjugué
    Cette CD27 protéine est marqué à la Fc Tag.
    Séquence
    AA 21-192
    Attributs du produit
    This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 45.9 kDa. The protein migrates as 45-65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
    Pureté
    >95 % as determined by SDS-PAGE.
    Stérilité
    0.22 μm filtered
    niveau d'endotoxine
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product CD27 Protéine
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    50 mM Tris, 100 mM Glycine, pH 7.5
    Conseil sur la manipulation
    Please avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
  • Antigène
    CD27 (CD27 Molecule (CD27))
    Autre désignation
    CD27 (CD27 Produits)
    Synonymes
    TNFRSF7 Protein, S152 Protein, Tnfrsf7 Protein, Tp55 Protein, S152. LPFS2 Protein, T14 Protein, CD27 molecule Protein, CD27 antigen Protein, CD27 Protein, Cd27 Protein
    Sujet
    CD Antigen CD27 is also known as Tumor necrosis factor receptor superfamily member 7 (TNFRSF7), which belongs to TNF-receptor superfamily. CD27 / TNFRSF7 is found in most T-lymphocytes. CD27 / TNFRSF7 is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-κB and MAPK8/JNK. CD27 has been shown to interact with SIVA1, TRAF2 and TRAF3.
    Poids moléculaire
    45.9 kDa
    NCBI Accession
    NP_001233
    Pathways
    Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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