CD27 Protein (AA 24-182) (mFc Tag)
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- Antigène Voir toutes CD27 Protéines
- CD27 (CD27 Molecule (CD27))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 24-182
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Origine
- Souris
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette CD27 protéine est marqué à la mFc Tag.
- Fonction
- Mouse CD27/NFRSF7 Protein
- Séquence
- Pro24-Arg182
- Attributs du produit
- Recombinant Mouse CD27/NFRSF7 Protein is expressed from HEK293 with mFc (IgG1) tag at the C-Terminus.It contains Pro24-Arg182.
- Pureté
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Stérilité
- 0.22 μm filtered
- niveau d'endotoxine
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Mouse CD27, mFc Tag at 1μg/ml (100μl/Well) on the plate. Dose response curve for Mouse CD27 Ligand, hFc Tag with the EC50 of 10.3ng/ml determined by ELISA. See testing image for detail.
- Top Product
- Discover our top product CD27 Protéine
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- CD27 (CD27 Molecule (CD27))
- Autre désignation
- CD27 (CD27 Produits)
- Synonymes
- TNFRSF7 Protein, S152 Protein, Tnfrsf7 Protein, Tp55 Protein, S152. LPFS2 Protein, T14 Protein, CD27 molecule Protein, CD27 antigen Protein, CD27 Protein, Cd27 Protein
- Sujet
- CD27, also known as TNFRSF7, is an approximately 55 kDa transmembrane protein in the TNF receptor superfamily. It functions as a co-stimulatory molecule that supports lymphocyte activation and survival. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis.
- Poids moléculaire
- 44.3 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result.
- Pathways
- Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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