CD27 Protein (AA 20-191) (Fc Tag)

N° du produit ABIN7274100

Détail du produit

Antigène: CD27 (CD27 Molecule (CD27))

Type de proteíne: Recombinant

Attributs du protein: AA 20-191

Origine: Macaque rhésus, Cynomolgus

Source: HEK-293 Cells

Purification/Conjugué: Cette CD27 protéine est marqué à la Fc Tag.

Fonction: Cynomolgus/Rhesus macaque CD27/TNFRSF7 Protein

Séquence: Ala20-Arg191

Attributs du produit: Recombinant Cynomolgus/Rhesus macaque CD27/TNFRSF7 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Ala20-Arg191.

Pureté: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1EU per μg by the LAL method.

Biological Activity Comment: Immobilized Cynomolgus CD27 Ligand, His Tag at 2μg/ml (100μl/well) on the plate. Dose response curve for Cynomolgus/Rhesus macaque CD27, hFc Tag with the EC50 of 41.5ng/ml determined by ELISA. See testing image for detail.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: CD27 (CD27 Molecule (CD27))

Autre désignation: CD27 (CD27 Produits)

Synonymes: TNFRSF7 Protein, S152 Protein, Tnfrsf7 Protein, Tp55 Protein, S152. LPFS2 Protein, T14 Protein, CD27 molecule Protein, CD27 antigen Protein, CD27 Protein, Cd27 Protein

Sujet: CD27, also known as TNFRSF7, is an approximately 55 kDa transmembrane protein in the TNF receptor superfamily. It functions as a co-stimulatory molecule that supports lymphocyte activation and survival. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis.

Poids moléculaire: 46.5 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result.

NCBI Accession: XP_005569963

Pathways: Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints