CD27 Protein (His tag,Fc Tag)

N° du produit ABIN7320754

Détail du produit

Antigène: CD27 (CD27 Molecule (CD27))

Type de proteíne: Recombinant

Origine: Souris

Source: Human Cells

Purification/Conjugué: Cette CD27 protéine est marqué à la His tag,Fc Tag.

Fonction: Recombinant Mouse CD27/TNFRSF7 Protein (Fc & His Tag)

Séquence: Pro24-Arg182

Attributs du produit: Recombinant Mouse CD27 antigen is produced by our Mammalian expression system and the target gene encoding Pro24-Arg182 is expressed with a Fc, 6His tag at the C-terminus.

Pureté: > 95 % as determined by SDS-PAGE

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: CD27 (CD27 Molecule (CD27))

Autre désignation: CD27/TNFRSF7 (CD27 Produits)

Synonymes: TNFRSF7 Protein, S152 Protein, Tnfrsf7 Protein, Tp55 Protein, S152. LPFS2 Protein, T14 Protein, CD27 molecule Protein, CD27 antigen Protein, CD27 Protein, Cd27 Protein

Sujet:

Background: Mouse CD27 is a single-pass type I membrane protein which is a member of the tumor necrosis factor receptor superfamily. CD27 is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. CD27 transduces signals that lead to the activation of NF-κB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.

Synonym: CD27 antigen, CD27L receptor, T-cell activation antigen CD27, Tumor necrosis factor receptor superfamily member 7,S152,Tnfrsf7,Tp55

Poids moléculaire: 45.8 kDa

NCBI Accession: NP_001028298

Pathways: Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints