FZD4 Protein (AA 37-180) (Fc Tag)

N° du produit ABIN2181126

Détail du produit

Antigène: FZD4 (Frizzled Family Receptor 4 (FZD4))

Type de proteíne: Recombinant

Attributs du protein: AA 37-180

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette FZD4 protéine est marqué à la Fc Tag.

Séquence: AA 37-180

Attributs du produit: This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 42.9 kDa. The protein migrates as 50-65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Pureté: >95 % as determined by SDS-PAGE.

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1.0 EU per μg by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: PBS, pH 7.4

Conseil sur la manipulation: Please avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).

Détail du antigène

Antigène: FZD4 (Frizzled Family Receptor 4 (FZD4))

Autre désignation: Frizzled-4 (FZD4 Produits)

Synonymes: CG4626 Protein, DFz4 Protein, Dfz4 Protein, Dm Fz4 Protein, Dmel\\CG4626 Protein, Fz4 Protein, anon-WO0170980.10 Protein, anon-WO0170980.11 Protein, fz1 Protein, zg01 Protein, CD344 Protein, EVR1 Protein, FEVR Protein, FZD4S Protein, Fz-4 Protein, FzE4 Protein, GPCR Protein, hFz4 Protein, frizzled4 Protein, fz4 Protein, FZ-4 Protein, frizzled 4 Protein, frizzled class receptor 4 Protein, frizzled-4 Protein, frizzled class receptor 4 S homeolog Protein, fz4 Protein, fzd4 Protein, Tsp_10376 Protein, FZD4 Protein, Fzd4 Protein, fzd4.S Protein

Sujet: Frizzled-4 (FZD4) is also known as FzE4, CD344, which belongs to the G-protein coupled receptor Fz/Smo family. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. FZD4 contains one FZ (frizzled) domain. FZD4 may be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. FZD4 interacts with MAGI3 and norrin (NDP).

Poids moléculaire: 42.9 kDa

Pathways: Signalisation WNT, Hormone Transport, Sensory Perception of Sound