NLRP1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

N° du produit ABIN2713167

Détail du produit

Antigène: NLRP1 (NLR Family, Pyrin Domain Containing 1 (NLRP1))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 1

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette NLRP1 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human CARD7 / NLRP1 (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: NLRP1 (NLR Family, Pyrin Domain Containing 1 (NLRP1))

Autre désignation: Card7,nlrp1 (NLRP1 Produits)

Synonymes: CARD7 Protein, CIDED Protein, CLR17.1 Protein, DEFCAP Protein, DEFCAP-L/S Protein, NAC Protein, NALP1 Protein, PP1044 Protein, SLEV1 Protein, VAMAS1 Protein, NLR family pyrin domain containing 1 Protein, NLRP1 Protein, Nlrp1 Protein

Sujet: This gene encodes a member of the Ced-4 family of apoptosis proteins. Ced-family members contain a caspase recruitment domain (CARD) and are known to be key mediators of programmed cell death. The encoded protein contains a distinct N-terminal pyrin-like motif, which is possibly involved in protein-protein interactions. This protein interacts strongly with caspase 2 and weakly with caspase 9. Overexpression of this gene was demonstrated to induce apoptosis in cells. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity of some variants has not been determined.

Poids moléculaire: 165.7 kDa

NCBI Accession: NP_127497

Pathways: Positive Regulation of Endopeptidase Activity, Inflammasome