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ASAH1 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

ASAH1 Origine: Humain Hôte: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
N° du produit ABIN2714319
  • Antigène Voir toutes ASAH1 Protéines
    ASAH1 (N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 (ASAH1))
    Type de proteíne
    Recombinant
    Attributs du protein
    Transcript Variant 2
    Origine
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain
    Source
    • 4
    • 4
    • 2
    • 2
    HEK-293 Cells
    Purification/Conjugué
    Cette ASAH1 protéine est marqué à la Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Attributs du produit
    • Recombinant human Acid ceramidase (transcript variant 2) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Pureté
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product ASAH1 Protéine
  • Indications d'application
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Commentaires

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Stock
    -80 °C
    Stockage commentaire
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Antigène
    ASAH1 (N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 (ASAH1))
    Autre désignation
    Acid Ceramidase (ASAH1 Produits)
    Synonymes
    AC Protein, ACDase Protein, ASAH Protein, PHP Protein, PHP32 Protein, SMAPME Protein, 2310081N20Rik Protein, Asah Protein, MGC82286 Protein, asah1 Protein, zgc:101637 Protein, ASAH1 Protein, zgc:66026 Protein, N-acylsphingosine amidohydrolase 1 Protein, N-acylsphingosine amidohydrolase (acid ceramidase) 1 Protein, N-acylsphingosine amidohydrolase (acid ceramidase) 1 L homeolog Protein, N-acylsphingosine amidohydrolase (acid ceramidase) 1a Protein, Acid ceramidase Protein, N-acylsphingosine amidohydrolase (acid ceramidase) 1b Protein, ASAH1 Protein, Asah1 Protein, asah1.L Protein, asah1a Protein, asah-1 Protein, asah1b Protein
    Sujet
    This gene encodes a member of the acid ceramidase family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. Processing of this preproprotein generates alpha and beta subunits that heterodimerize to form the mature lysosomal enzyme, which catalyzes the degradation of ceramide into sphingosine and free fatty acid. This enzyme is overexpressed in multiple human cancers and may play a role in cancer progression. Mutations in this gene are associated with the lysosomal storage disorder, Farber lipogranulomatosis, and a neuromuscular disorder, spinal muscular atrophy with progressive myoclonic epilepsy.
    Poids moléculaire
    46.3 kDa
    NCBI Accession
    NP_004306
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