eIF4EBP1 Protein (His tag)

N° du produit ABIN2720101

Détail du produit

Antigène: eIF4EBP1 (EIF4EBP1) (Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette eIF4EBP1 protéine est marqué à la His tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human EIF4EBP1 / 4E-BP1 protein expressed in E. coli.
• Produced with end-sequenced ORF clone

Pureté: > 95 % as determined by SDS-PAGE and Coomassie blue staining

niveau d'endotoxine: < 0.1 EU per μg protein as determined by LAL test

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Buffer: Lyophilized from a 0.2 μM filtered solution of 20 mM Phosphate buffer, 150 mM NaCl, pH 7.4. Stable for at least 6 months from date of receipt under proper storage and handling conditions.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: eIF4EBP1 (EIF4EBP1) (Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1))

Autre désignation: Eif4ebp1,4e-Bp1 (EIF4EBP1 Produits)

Synonymes: 4E-BP1 Protein, 4EBP1 Protein, BP-1 Protein, PHAS-I Protein, 4e-bp1 Protein, AA959816 Protein, 153432_at Protein, 43-BP Protein, 4E-BP Protein, 4EBP Protein, 4e-bp Protein, 4eBP Protein, 4ebp Protein, BcDNA.HL08053 Protein, BcDNA:HL08053 Protein, CG8846 Protein, CT8705 Protein, Dm 4E-BP Protein, Dmel\\CG8846 Protein, Phas1 Protein, Thor/EIF4EBP Protein, anon-WO0172774.158 Protein, d4E-BP Protein, d4E-BP1 Protein, d4EBP Protein, d4e-bp Protein, d4eBP Protein, dthor Protein, eIF4E-BP Protein, l(2)06270 Protein, l(2)k07736 Protein, l(2)k13517 Protein, pp20 Protein, thor Protein, EIF4EBP1 Protein, fc04h09 Protein, wu:fc04h09 Protein, zgc:64137 Protein, eukaryotic translation initiation factor 4E binding protein 1 Protein, CG8846 gene product from transcript CG8846-RA Protein, EIF4EBP1 Protein, Eif4ebp1 Protein, Thor Protein, eif4ebp1 Protein

Sujet: This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.

Poids moléculaire: 14.7 kDa

NCBI Accession: NP_004086

Pathways: Signalisation MAPK, Signalisation PI3K-Akt, Signalisation RTK, AMPK Signaling, Regulation of Cell Size, BCR Signaling